Results 131 to 140 of about 29,893 (236)

Rapid normal fibroblast‐tumor crosstalk promotes cancer‐associated fibroblast‐like activation and attenuates mitomycin C cytotoxicity in bladder cancer

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Normal bladder fibroblasts rapidly engage in bidirectional crosstalk with bladder cancer cells, acquiring cancer‐associated fibroblast‐like activation features while promoting wound closure, epithelial‐mesenchymal transition‐like cadherin remodeling, and reduced mitomycin C‐induced cytotoxicity.
Jinhui Gao, Cindy Xinyu Ji, Ci Ren, John Hines, Eleanor Stride, Richard T. Bryan, Jennifer L. Rohn   +6 more
wiley   +1 more source

Generation of Ctcf knockout mice.

, 2013
(A) A schematic diagram of the mouse Ctcf locus and the targeting vector derived from the wild type Ctcf allele as described in Materials and Methods are shown. E1–E12 denote Ctcf exons 1 through 12.
Leslie E. Smith (325571), Christopher J. Kemp (221372), Natalia A. Rabaia (169544), Galina N. Filippova (169552), Kay Gurley (325573), Sara Fagerlie (325572), James M. Moore (169541), Victor V. Lobanenkov (325576), Dmitry Loukinov (325574), Steven J. Collins (325575), Christine M. Disteche (50498)   +10 more
core   +1 more source

A Review of Senescence‐Associated Secretory Phenotype‐Mediated Remodeling of the Tumor Microenvironment: Implications for Cancer Progression and Therapy

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Cellular senescence influences cancer progression through irreversible cell‐cycle arrest, immune surveillance, and paracrine signaling mediated by the senescence‐associated secretory phenotype (SASP). SASP comprises inflammatory cytokines, chemokines, growth factors, and matrix‐remodeling enzymes that regulate the tumor ...
Sneha Pallatt, Sibin Nambidi, Antara Banerjee, Surajit Pathak   +3 more
wiley   +1 more source

Basic overview of the CTCF core and auxiliary motives described in Nakahashi et al "A genome-wide map of CTCF multivalency redefines the CTCF code"

, 2018
Brief overview of the CTCF motifs described in Nakahashi et al "A genome-wide map of CTCF multivalency redefines the CTCF code" (Cell Rep 2013, doi: 10.1016/j.celrep.2013.04.024, https://www.ncbi.nlm.nih.gov/pubmed/23707059)
Wolfgang Resch (5872724)
core   +1 more source

Eating Behavior, Food Consumption Frequency, and Nutritional Status Among Undergraduate Nursing Students: A Cross‐Sectional Study

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
In a cross‐sectional study of 61 undergraduate nursing students in Brazil, dietary patterns were centered on rice, beans, and bread, with limited fruit and vegetable diversity and frequent coffee consumption (72.1% daily or weekly). Despite a predominantly eutrophic BMI profile (65.0%), eating behavior (TFEQ‐21 domains: Cognitive Restraint ...
Maria Laura Lacerda Nascimento, Aline Nataly Soares Vital, Taisy Cinthia Ferro Cavalcante, Emily Pereira de Souza, Amanda Alves Marcelino da Silva   +4 more
wiley   +1 more source

CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis

Genome Biology
Background CTCF is considered as the most essential transcription factor regulating chromatin architecture and gene expression. However, genome-wide impact of CTCF on erythropoiesis has not been extensively investigated.
Xue Yang, Li Cheng, Ye Xin, Jianxiang Zhang, Xinfeng Chen, Jinchao Xu, Mengli Zhang, Ruopeng Feng, Judith Hyle, Wenjie Qi, Wojciech Rosikiewicz, Beisi Xu, Chunliang Li, Peng Xu   +13 more
doaj   +1 more source

DNA Replication Stress‐Induced Transcriptome of Human Burkitt's Lymphoma Identifies Reciprocal Regulation Between MBD1 and BCL6 During Germinal Center‐Derived B‐Lymphomagenesis

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT BCL6 is a master transcriptional regulator of germinal center (GC) B cells. BCL6 is frequently translocated at the major translocation cluster (MTC) within intron 1 of the BCL6 locus, a hotspot commonly rearranged in diffuse large B cell lymphomas (DLBCLs).
Santosh Kumar Gothwal, Kyoko Oichai, Hongtae Kim, Kyungjae Myung, Jacqueline H. Barlow   +4 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, Volume 3, Issue 3, September 2026.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, Volume 270, Issue 1, Page 83-97, September 2026.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Characterization of the molecular interactions between Kaiso and CTCF using AlphaFold2 and molecular dynamics simulations

Bibechana
CCCTC-binding factor (CTCF) is an architectural protein that plays a crucial role in global chromatin organization and remodeling via its interaction with several protein partners.
Bidhya Thapa, Narayan Prasad Adhikari
doaj   +1 more source