Results 151 to 160 of about 23,645 (194)

<i>ROBO2</i> Variants Associated With Atrial Septal Defect Define a Novel Regulatory Element. [PDF]

Circ Genom Precis Med
Kim SW, Parfenov M, Rodriguez-Murillo L, Conner DA, Sharma A, Peter I, Xiao F, Layton O, Tai A, Ward T, Wasson LK, Gorham JM, Mazaika E, Lagomarsino VN, Young-Pearse TL, Goldmuntz E, Wakimoto H, Agopian AJ, McKean DM, DePalma SR, Pu WT, Seidman CE, Gelb BD, Seidman JG, PCGC Investigators.   +24 more
europepmc   +1 more source

Touched by CTCF.

, 2008
openaire   +1 more source

Methadone Maintenance Treatment vs. Long-Term Abstinence Without Opioid Agonist: Epigenome-Wide Study of DNA Methylation. [PDF]

Epigenomes
Levran O, Li J, Sason A, Adelson M, Peles E.   +4 more
europepmc   +1 more source

Clostridioides difficile TcdB induces expression of its receptor (CSPG4) through a noncanonical Hippo signaling mechanism. [PDF]

J Biol Chem
Larabee JL, Donald EJ, Sukhadia AA, Shadid TM, Miller SJ, Ballard JD.   +5 more
europepmc   +1 more source

Silencing of BCL11A by disrupting enhancer-dependent epigenetic insulation.

Blood
Wang K, Wang J, Feng R, Dudnyk K, Kim YJ, Lim JYS, Lee M, Zhang Y, Gao X, Cheng Y, Orkin SH, Zhou J, Weiss MJ, Yue F, Xu J.   +14 more
europepmc   +1 more source

Role of CTCF in DNA damage response [PDF]

Mutation Research - Reviews in Mutation Research, 2019
CCCTC-binding factor (CTCF) is a highly conserved, ubiquitously expressed zinc finger protein. CTCF is a multifunctional protein, associated with a number of vital cellular processes such as transcriptional activation, repression, insulation, imprinting and genome organization.
Vinay Singh Tanwar, Cynthia C JOSÉ, Suresh Cuddapah   +2 more
exaly   +3 more sources

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Embryogenesis without CTCF in flies and vertebrates

Nature Structural & Molecular Biology, 2021
CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails embryogenesis in zebrafish and Drosophila melanogaster, revealing contrasting effects across species.
Geoffrey Fudenberg, Elphège P. Nora
openaire   +2 more sources

The tumor suppressor role of CTCF

Journal of Cellular Physiology, 2011
AbstractCTCF is an evolutionary conserved and ubiquitously expressed protein that binds thousands of sites in the human genome. Ectopic expression of CTCF in various normal and tumoral human cell lines inhibits cell division and clonogenicity, with the consequence to consider CTCF a potential tumor‐suppressor factor.
Fiorentino, Francesco Paolo, Giordano, Antonio   +1 more
openaire   +4 more sources

Regulation of 3D chromatin organization by CTCF

Current Opinion in Genetics & Development, 2021
Studies of nuclear architecture using chromosome conformation capture methods have provided a detailed view of how chromatin folds in the 3D nuclear space. New variants of this technology now afford unprecedented resolution and allow the identification of ever smaller folding domains that offer new insights into the mechanisms by which this ...
Jian-Feng Xiang, Victor G Corces
openaire   +2 more sources

Expression of chicken CTCF gene in COS-1 cells and partial purification of CTCF protein

Biochemistry (Moscow), 2013
The chicken gene for transcription factor CTCF was expressed in COS-1 mammalian cells. The CTCF protein containing polyhistidine tag was partially purified using metallo-affinity and ion-exchange chromatography. The expressed protein localized in the cell nucleus and was shown to be functionally active in the electrophoretic mobility shift assay and ...
E S, Kotova, I V, Sorokina, S B, Akopov, L G, Nikolaev, E D, Sverdlov   +4 more
openaire   +2 more sources