Results 31 to 40 of about 29,893 (236)
Epigenetics, 2018 DNA methylation can affect tissue-specific gene transcription in ways that are difficult to discern from studies focused on genome-wide analyses of differentially methylated regions (DMRs). To elucidate the variety of associations between differentiation-
Carl Baribault +5 more
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CTCF-mediated genome organization and leukemogenesis [PDF]
Leukemia, 2020 Recent technological advancements and genome-wide studies provide compelling evidence that dynamic chromatin interaction and three-dimensional genome organization in nuclei play an important role in regulating gene expression. Mammalian genomes consist of many small functional domains termed topologically associated domains (TADs), many of them ...
Yi Qiu, Suming Huang
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CCCTC-binding factor recruitment to the early region of the human papillomavirus type 18 genome regulates viral oncogene expression [PDF]
, 2015 C.P. was supported by a Ph.D. studentshipfunded by the University of St. Andrews, School of Medicine. I.P. is supported by a Cancer Research UK (CRUK) Ph.D. studentship awarded to J.L.P. and S.R. I.G. and N.C.
Coleman, Nicholas +9 more
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Journal of Hepatocellular Carcinoma, 2021 Haoming Mai,* Haisheng Xie,* Jia Hou,* Haitao Chen, Bin Zhou, Jinlin Hou, Deke Jiang State Key Laboratory of Organ Failure Research, Guangdong Key Laboratory of Viral Hepatitis Research, Guangdong Institute of Liver Diseases, Department of ...
Mai H +6 more
doaj
Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites. [PDF]
PLoS ONE, 2010 The conserved 11 zinc-finger protein CTCF is involved in several transcriptional mechanisms, including insulation and enhancer blocking. We had previously identified two composite elements consisting of a CTCF and a TR binding site at the chicken ...
Oliver Weth +5 more
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CTCF as a boundary factor for cohesin-mediated loop extrusion: evidence for a multi-step mechanism
Nucleus, 2020 Mammalian genome structure is closely linked to function. At the scale of kilobases to megabases, CTCF and cohesin organize the genome into chromatin loops.
Anders S. Hansen
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Role of CTCF poly(ADP-Ribosyl)ation in the regulation of apoptosis in breast cancer cells
Indian Journal of Medical and Paediatric Oncology, 2015 Introduction: CTCF is a candidate tumor suppressor gene encoding a multifunctional transcription factor. CTCF function is controlled by posttranslational modification and interaction with other proteins. Research findings suggested that CTCF function can
Bhooma Venkatraman, Elena Klenova
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CTCF regulates the local epigenetic state of ribosomal DNA repeats
Epigenetics & Chromatin, 2010 Background CCCTC binding factor (CTCF) is a highly conserved zinc finger protein, which is involved in chromatin organization, local histone modifications, and RNA polymerase II-mediated gene transcription.
van de Nobelen Suzanne +14 more
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Clustered CTCF binding is an evolutionary mechanism to maintain topologically associating domains
Genome Biology, 2020 Background CTCF binding contributes to the establishment of a higher-order genome structure by demarcating the boundaries of large-scale topologically associating domains (TADs).
Elissavet Kentepozidou +7 more
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Genome-wide Analysis of Ctcf-RNA Interactions
, 2014 Ctcf is a "master regulator" of the genome that plays a role in a variety of gene regulatory functions as well as in genome architecture. Evidence from studying the epigenetic process of X-chromosome inactivation suggests that, in certain cases, Ctcf ...
Kung, Johnny
core +6 more sources