Results 21 to 30 of about 45,922 (120)
Indian Journal of Pathology and Microbiology, 2020 Background: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer worldwide. It is essential to develop methods for the accurate diagnosis of PTC to avoid unnecessary surgery.
Sang Ah Lee +4 more
doaj +1 more source
Pharmaceuticals, 2020 CXC chemokine receptor 7 (CXCR7) is a G-protein-coupled receptor that signals through the β-arrestin pathway. Its ligands include interferon-inducible T cell α chemoattractant (CXCL11) and stromal cell-derived factor-1 (CXCL12).
Nicole Lounsbury
doaj +1 more source
Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function. [PDF]
PLoS ONE, 2017 Recent evidence suggests that chemokine CXCL12, the cognate agonist of chemokine receptors CXCR4 and ACKR3, reduces thrombin-mediated impairment of endothelial barrier function.
You-Hong Cheng +4 more
doaj +1 more source
NLRP3 Regulated CXCL12 Expression in Acute Neutrophilic Lung Injury
Journal of Inflammation Research, 2020 Yanwen Peng,1 Qiongli Wu,2 Hao Tang,3 Jingrou Chen,1 Qili Wu,1 Xiaofeng Yuan,4 Shiqiu Xiong,5 Yujin Ye,6 Haijin Lv7 1The Biotherapy Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, People’s Republic of China ...
Peng Y +8 more
doaj
PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells. [PDF]
PLoS ONE, 2013 Despite significant progress, the molecular mechanisms responsible for pancreatic beta cell depletion and development of diabetes remain poorly defined. At present, there is no preventive measure against diabetes. The positive impact of CXCL12 expression
Jelena Marković +9 more
doaj +1 more source
Frontiers in Neuroscience, 2023 BackgroundC-X-C motif chemokine 12 (CXCL12) is a chemokine that performs many functions. Studies have shown that CXCL12 can aggravate inflammatory symptoms in the central nervous system (CNS). Evidence also indicates that CXCL12 can promote the repair of
Dahe Lin +13 more
doaj +1 more source
Clinical and Experimental Hypertension, 2017 Objective: We investigated whether the CXCL12-801G/A polymorphism was associated with preeclampsia (PE) susceptibility in a Chinese Han population. Methods: We examined 912 PE women and 1025 controls for the CXCL12-801G/A polymorphism by polymerase chain
Jine Xu +6 more
doaj +1 more source
The CXCL12/CXCR7 signaling axis, isoforms, circadian rhythms, and tumor cellular composition dictate gradients in tissue. [PDF]
PLoS ONE, 2017 Chemokine CXCL12 gradients drive chemotaxis in a CXCR4-dependent mechanism and have been implicated in cancer metastasis. While CXCL12 gradients are typically studied in organized, defined environments, the tumor microenvironment is disorganized. In vivo,
Phillip C Spinosa +3 more
doaj +1 more source
Neuropsychiatric Disease and Treatment, 2023 Miaomiao Han,1,2 Bo Ma,3 Ruifang She,4 Yan Xing,5 Xiaohong Li1 1Department of Neurology, Jinan Central Hospital, Shandong University, Jinan City, People’s Republic of China; 2Encephalopathy Department, Zibo Hospital of Integrated Traditional Chinese and ...
Han M, Ma B, She R, Xing Y, Li X
doaj
Function of chemokine (CXC motif) ligand 12 in periodontal ligament fibroblasts. [PDF]
PLoS ONE, 2014 The periodontal ligament (PDL) is one of the connective tissues located between the tooth and bone. It is characterized by rapid turnover. Periodontal ligament fibroblasts (PDLFs) play major roles in the rapid turnover of the PDL.
Yuichi Yashiro +5 more
doaj +1 more source