Journal of Periodontology, Volume 96, Issue 12, Page 1391-1399, December 2025.Abstract Background The present study aimed to investigate the expression of stromal cell‐derived factor‐1 (SDF‐1) after tooth extraction in rats and its regulatory effect on the expression of osteopontin (OPN) and vascular endothelial growth factor (VEGF).
Jingjing Kong +5 more
wiley +1 more source
Evaluation of the role of downregulation of SNF5/INI1 core subunit of SWI/SNF complex in clear cell renal cell carcinoma development [PDF]
, 2017 Clear cell renal cell carcinoma (ccRCC) is characterized by stabilization of hypoxia-inducible factor (HIF1), and mutations in von Hippel-Lindau (VHL) gene.
Chrzan, A. +16 more
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Stem cells migration during skeletal muscle regeneration - the role of Sdf-1/Cxcr4 and Sdf-1/ Cxcr7 axis [PDF]
, 2016 The skeletal muscle regeneration occurs due to the presence of tissue specific stem cells - satellite cells. These cells, localized between sarcolemma and basal lamina, are bound to muscle fibers and remain quiescent until their activation upon muscle ...
Brzoska, Edyta +12 more
core +2 more sources
Applications of Lysosome‐Targeting Receptors (LTRs) in Targeted Protein Degradation
MedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.Targeted protein degradation based on LYTAC technology has recently emerged as a research hotspot in various diseases. The membrane receptors recently utilized in LYTAC design are summarized in this article, with insights into current strategies, challenges, and prospects for LYTAC‐based technologies.
Lijian Shen +4 more
wiley +1 more source
Peripheral regulatory cells immunophenotyping in Primary Sjögren's Syndrome: a cross-sectional study [PDF]
, 2013 INTRODUCTION: IL-10--producing B cells, Foxp3-expressing T cells (Tregs) and the IDO-expressing dendritic cells (pDC) are able to modulate inflammatory processes, to induce immunological tolerance and, in turn, to inhibit the pathogenesis of autoimmune ...
Gabriela Hernández-Molina +5 more
core +1 more source
The Aging Landscape by scRNAseq of Mesenchymal Lineage Cells in Mouse Bone
Aging Cell, Volume 24, Issue 12, December 2025.scRNA‐seq analysis reveals age‐related changes in bone mesenchymal cells in male and female mice. Moreover, the comparison of aging and autophagy deficiency in bone mesenchymal cells shows overlap and suggests that age‐related decline in autophagy contributes to skeletal aging.
Melda Onal +12 more
wiley +1 more source
Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. [PDF]
, 2014 The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential.
A Boucharaba +72 more
core +3 more sources
Gene expression profiling of Ewing sarcoma tumours reveals the prognostic importance of tumour–stromal interactions: a report from the Children's Oncology Group [PDF]
, 2015 Relapse of Ewing sarcoma (ES) can occur months or years after initial remission, and salvage therapy for relapsed disease is usually ineffective. Thus, there is great need to develop biomarkers that can predict which patients are at risk for relapse so ...
Abdel-Wahab +51 more
core +1 more source
CXCR7 Transactives and Triggers Signaling through EGFR [PDF]
Journal of Neoplasm, 2016 Over expression of chemokine receptors such as CXCR7 is a common hallmark of various cancers. Recent evidence suggests that CXCR7 interacts with the epidermal growth factor receptor (EGFR) to activate downstream mitogenic signaling and proliferation in tumour cells. Few current therapies directly target CXCR7; however, targeting the interaction between
openaire +1 more source
Progress of anti-angiogenic therapy for brain tumors: new modality and resolution of the resistance [PDF]
, 2012 科学研究費助成事業(科学研究費補助金)研究成果報告書：基盤研究(B)2009-2011課題番号 ...
TAKANO SHINGO, 高野 晋吾
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