Results 111 to 120 of about 6,925 (209)
CXCR7 functions as a scavenger for CXCL12 and CXCL11 [PDF]
, 2019 Background: CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses. The function
Pruenster, Monika +7 more
core
Expression of CXCR7 in hippocampal cells after hypoxia.
, 2013 Adhered hippocampal cells were exposed to hypoxia or normoxia (control), and then CXCR7 expression was determined by immunofluorescence and western blot at 0.5, 1, 12, 24, and 36 h after hypoxia.
Xuefei Han (278603) +5 more
core +1 more source
Role of CXCR7 in Human Coronary Artery Smooth Muscle Restenosis [PDF]
, 2019 Objective—Whether CXCR7 is a signaling or non-signaling scavenger receptor is still in debate. Our previous study showed that during monocyte-to-macrophage differentiation, CXCR7 mediates positive signaling to the p38 and JNK, but not the ERK1/2 ...
Alqurashi, Thamer
core
CXCR7 in relation to clinicopathological features.
, 2014 CXCR7 in relation to clinicopathological features.
Malgorzata Walentowicz-Sadlecka (507881) +7 more
core +1 more source
Funktion und Regulation des Chemokinrezeptors CXCR7 [PDF]
, 2013 Der Chemokinrezeptor CXCR7 spielt eine essentielle Rolle bei der normalen Entwicklung und fördert die Initiation und Progression verschiedener pathologischer Prozesse wie Krebs und Autoimmunerkrankungen.
Hoffmann, Frauke
core
Expression of CXCL12, CXCR7 and CXCR7 mRNA during nephrogenesis.
, 2012 Mapping of CXCL12, CXCR7, and CXCR4 expression was performed using the markers WT1 (dual in situ hybridization) and Podocin as well as VEGFR-2 (dual immunofluorescence). +, strong expression; (+) weak expression; (−) very weak expression; − no expression.
Wiebke Mueller (144965) +8 more
core +1 more source
CXCR7+ EC are not contact inhibited.
, 2013 (A) pLEC were infected with Trans only or Trans+CXCR7. At 20 hours post-infection cells were trypsinized, counted and replated onto chamber slides at confluence and allowed to attach for a further 20 hours. Resulting monolayers were fixed and stained for
Jessica M. Osborn (436508) +4 more
core +1 more source
CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells.
, 2014 Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and everolimus.
Grimaldi A +16 more
core +1 more source
A patent review of CXCR7 modulators (2019-present)
Expert Opinion on Therapeutic PatentsAtypical chemokine receptor 3 (ACKR3) (formerly CXCR7) regulates various biological processes through its ligands and is closely associated with numerous diseases, including inflammation, cancer, cardiovascular diseases (CVDs), pain, and neurological disorders.
Thanigaimalai Pillaiyar, Stefan Laufer
openaire +2 more sources
CRISPR/Cas9-mediated Gene Editing to Assess the Role of CXCR7 in Cervical Cancer
, 2021 Objective: Chemokine receptors and their corresponding chemokine ligands play a significant role in tumor cell survival and proliferation. CXCR7 is a receptor often overexpressed in different cancers including cervical cancer; however, its exact role in ...
Alqahtani, Saud
core