Results 91 to 100 of about 6,925 (209)
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li +5 more
wiley +1 more source
CXCR7/CXCR3 tail switch alters ubiquitination properties of the receptors.
, 2012 (A) Immunoprecipitation experiments were performed in cells expressing chimeric receptors consisting on CXCR7 with CXCR3 C-terminus (CXCR7-X3) or the reciprocal CXCR3 with CXCR7 C-terminus (CXCR3-X7).
Meritxell Canals (175821) +5 more
core +1 more source
CXCR7 limits interaction of CXCR4 and β-arrestin 2 in CXCR4+-CXCR7+ cells.
, 2014 (A and B) Model outputs for CXCL12-dependent recruitment of β-arrestin 2 specifically to CXCR4 (A) or CXCR7 (B) in CXCR4+-CXCR7+ MDA-MB-231 cells. (C and D) Experimental data for recruitment of β-arrestin 2-CBC to CXCR4-CBRN (C) or CXCR7-CBGN (D) in ...
Nathaniel L. Coggins (572350) +7 more
core +1 more source
CXCR7 regulates multiple functions in HBMECs.
, 2014 A. shRNA-scramble CXCR7 or shRNA-CXCR7 HBMECs were seeded on 96 well plate in the presence of 200 ng/ml CXCL12 and cell proliferation was analyzed by XTT assay as described in “Materials and Methods”. B.
Kevin A. Walter (607333) +2 more
core +1 more source
The Role of Chemokine Receptor CXCR7 with EGFR in Breast Cancer Cell Proliferation [PDF]
, 2016 Recent advances have revealed a significant contribution of chemokines and their receptors in tumor growth, survival after chemotherapy and organ-specific metastasis.
Salazar, Nicole
core +3 more sources
High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma
World Journal of Surgical Oncology, 2012 Background Chemokines and their receptors are known to play important roles in the tumorigenesis of many malignancies. The aim of this study was to evaluate the prognostic impact of the expression of the chemokine SDF-1 and its receptors CXCR4 and CXCR7 ...
Wang Linhui +7 more
doaj +1 more source
Macrophage CXCR7: A Potential New Target for Atherosclerosis
, 2013 Objective—The discovery of CXCR7 as a new receptor for SDF-1 places many previously described SDF-1 functions attributed to CXCR4 in question, though whether CXCR7 acts as a signaling or “decoy” receptor has been in debate.
Ma, Wanshu
core
The role of chemokine receptor CXCR7 in lung cancer
Clinical Oncology and Cancer Research, 2010 OBJECTIVE To investigate whether CXCL12 and its receptor, CXCR7, play a role in lung cancer invasion and metastasis.METHODS Western blot and immunocytochemistry were used to detect CXCR7 protein expression in 8 lung cancer cell lines, EKVX, HOP62, HOP92, NCI-H23, NCI-H226, NCI-H322M, NCI-H446, and A549, and cell migration experiment was conducted to ...
Jun LIU +3 more
openaire +2 more sources
Stem Cell Research, 2017 CXCR4 and CXCR7 are prominent G protein-coupled receptors (GPCRs) for chemokine stromal cell-derived factor-1 (SDF-1/CXCL12). This study demonstrates that CXCR4 and CXCR7 induce differential effects during cardiac lineage differentiation and β-adrenergic
Delaine K. Ceholski +10 more
doaj +1 more source
Effect of CXCR7 receptor overexpression on U2932 DLBCL cells.
, 2018 (A) Quantification of CXCR7 expression by flow cytometry, in the total population of transfected U2932-CXCR7 and U2932-control cells or after measurements restricted only to GFP+ cells.
Miguel Alcoceba (3805117) +14 more
core +1 more source