Results 101 to 110 of about 6,925 (209)

Histological analysis of CXCR7-deficient kidneys.

, 2012
Kidney sections of E16.5 wildtype (A–C) and CXCR7 deficient littermates (D–F) were stained with periodic acid-Schiff (PAS) reagents. (A,D) Macroscopic images demonstrate that the overall kidney morphology is normal in the CXCR7 knockout embryo. (B,C,E,F)
Wiebke Mueller (144965), Ralf Stumm (144968), Sammy Haege (144953), Amelie Lupp (124205), Stefan Schulz (86207), Sandor Nietzsche (144966), Claudia Einer (144958), Stefanie Thiele (144963), Fabienne Mackay (144967)   +8 more
core   +1 more source

Mechanisms of CXCR7 induction in malignant melanoma development

Oncology Letters, 2017
Malignant melanoma (MM) is a highly malignant skin tumor. The mechanism of MM pathogenesis and its signaling pathways are not well characterized. C-X-C chemokine receptor type 7 (CXCR7) has been reported to regulate cancer cell invasion. The present study sought to investigate the effects of CXCR7 on MM development.
Li, Xiao-Jing, Liu, Pai, Tian, Wei-Wei, Li, Zhi-Feng, Liu, Bao-Guo, Sun, Jian-Fang   +5 more
openaire   +3 more sources

CXCR4 immunoreactivity in CXCR7 deficient kidneys.

, 2012
(A,B) In situ hybridizations with a radiolabeled CXCR4 probe show similar CXCR4 expression patterns and labeling intensities in the E14.5 kidney of a wildtype and a CXCR7 deficient mutant.
Wiebke Mueller (144965), Ralf Stumm (144968), Sammy Haege (144953), Amelie Lupp (124205), Stefan Schulz (86207), Sandor Nietzsche (144966), Claudia Einer (144958), Stefanie Thiele (144963), Fabienne Mackay (144967)   +8 more
core   +1 more source

2012 AACR Special Conference on Advances in Prostate Cancer Research

, 2012
CXCR7 was recently identified as the second member of the chemokine receptor family to bind stromal derived factor-1α (SDF-1α), a chemokine which is known to influence the establishment of cancer metastasis.
Kiss, Debra L., Windus, Louisa C. E., Avery, Vickey M.   +2 more
core   +1 more source

Identification of Entacapone as a Novel β-Arrestin 1 Biased Antagonist of CXCR7

Molecules
Background: The C-X-C chemokine receptor type 7 (CXCR7), also known as atypical chemokine receptor 3 (ACKR3), primarily signals through β-arrestin and plays a pivotal role in tumor progression, inflammation, and neurodegenerative diseases.
Liangrui Shi, Yan Huang, Lian Li, Huan Li, Xin Li, Zenghao Bi, Junke Liu, Sanyin Zhang, Zhaotong Cong, Bojun Wang, Shilin Chen   +10 more
doaj   +1 more source

Étude des mécanismes d'action du récepteur de chimiokine CXCR7/ACKR3 [PDF]

, 2018
Le récepteur de chimiokine CXCR7 découvert récemment a été identifié comme liant la chimiokine CXCL12, qui était, jusqu’à ce jour, considérée comme ligand exclusif du récepteur de chimiokine CXCR4 (Balabanian et al., 2005).
Gravel, Stéphanie
core  

Stimulation of TLR4 by LMW-HA Induces Metastasis in Human Papillary Thyroid Carcinoma through CXCR7

Clinical and Developmental Immunology, 2013
In inflammatory sites, high molecular weight hyaluronan fragments are degraded into lower molecular weight hyaluronan fragments (LMW-HA) to regulate immune responses. However, the function of LMW-HA in PTC progression remains to be elucidated.
Shipeng Dang, Yongde Peng, Lei Ye, Yanan Wang, Zhongqing Qian, Yuqing Chen, Xiaojing Wang, Yunzhi Lin, Xiaomei Zhang, Xiyan Sun, Qiong Wu, Yiji Cheng, Hong Nie, Min Jin, Huanbai Xu   +14 more
doaj   +1 more source

Stromal cell derived factor-1, CXCR4 and CXCR7 gene transcripts in pterygia

Journal of Current Ophthalmology, 2017
Purpose: Pterygium is a pathologic process with angiogenic and tumor cell like characteristics. Chemokine and chemokine receptors may contribute to the formation and growth of pterygia.
Shahram Bamdad, Behzad Khademi, Nooshin Chenari, Atta Taseh, Mahboobeh Razmkhah   +4 more
doaj   +1 more source

Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer

Molecular Oncology, 2018
Ovarian cancer (OC) is one of the most intractable diseases, exhibiting tremendous molecular heterogeneity and lacking reliable methods for screening, resulting in late diagnosis and widespread peritoneal dissemination.
Samira Benhadjeba, Lydia Edjekouane, Karine Sauvé, Euridice Carmona, André Tremblay   +4 more
doaj   +1 more source

CXCR7 influences the migration of B cells during maturation.

, 2014
The atypical chemokine receptor CXCR7 binds the chemokines CXCL12 and CXCL11. The receptor is widely expressed and was shown to tune CXCR12-induced responses of CXCR4.
Thelen M, Humpert ML, Jarrossay D, Pinto D   +3 more
core   +1 more source