Results 101 to 110 of about 10,649 (214)

Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. [PDF]

PLoS ONE, 2011
The link between inflammation and colorectal carcinoma has been acknowledged. However, the impact of bacterial lipopolysaccharide (LPS) binding to Toll-like receptor 4 (TLR4) on chemokine receptors in human colorectal carcinoma cells still remains to be ...
Huanbai Xu, Qiong Wu, Shipeng Dang, Min Jin, Jingwei Xu, Yiji Cheng, Minglin Pan, Yugang Wu, Chunhui Zhang, Yanyun Zhang   +9 more
doaj   +1 more source

Screening the Active Phytochemicals From Eclipta prostrata and Unraveling Their Molecular Insight Into Human Malignancies

Cancer Innovation, Volume 4, Issue 6, December 2025.
This review comprehensively analyses the phytochemicals from Eclipta prostrata, identifying 25 active compounds with chemotherapeutic potential against 15 different human malignancies. These compounds modulate diverse and complex mechanisms, including targeting critical signaling pathways (e.g., PI3K/AKT/mTOR), inducing regulated cell death (e.g., FAS,
Md. Sakhawat Hossain, Sanzida Khatun, Md Mojnu Mia, Fatematuz Zohora, Md. Rifat Sarker, K. M. Tanjida Islam, Md. Abu Sayeed, Moushumi Afroza Mou, Sherif Hamidu, Fatima Hamidu, A. M. Wasaf Hasan, Sanjida Mumtaj, Md Khaled Hossain, Md Sohel   +13 more
wiley   +1 more source

Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice [PDF]

, 2012
Background Tangential migration presents the primary mode of migration of cortical interneurons translocating into the cerebral cortex from subpallial domains.
Konstantinos Zarbalis, Youngshik Choe, Julie A Siegenthaler, Lori A Orosco, Samuel J Pleasure   +4 more
core   +3 more sources

CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells

Scientific Reports, 2017
Angiogenesis is the process by which new vessels form from existing vascular networks. Human umbilical vein endothelial cells (HUVECs) may contribute to the study of vascular repair and angiogenesis. The chemokine CXCL12 regulates multiple cell functions,
Min Zhang, Lisha Qiu, Yanyan Zhang, Dongsheng Xu, Jialin C. Zheng, Li Jiang   +5 more
doaj   +1 more source

High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma

World Journal of Surgical Oncology, 2012
Background Chemokines and their receptors are known to play important roles in the tumorigenesis of many malignancies. The aim of this study was to evaluate the prognostic impact of the expression of the chemokine SDF-1 and its receptors CXCR4 and CXCR7 ...
Wang Linhui, Chen Wei, Gao Li, Yang Qing, Liu Bing, Wu Zhenjie, Wang Yang, Sun Yinghao   +7 more
doaj   +1 more source

Activation and Long‐Term Maintenance of Adaptive Immunity in the Central Nervous System: A Double‐Edged Sword?

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
A wide spectrum of cells in the brain can engage in antigen presentation, which activates adaptive immunity in the central nervous system (CNS). Tissue‐resident memory T cells (TRM) develop in adaptive immunity in the CNS and provide long‐term immune surveillance, including the clearance of pathogens and tumor cells.
Luojinyun Wang, Feng Zhang, Jiehong Wu, Sibo Yang, Daqiang Zhou, Xiaodi Sun, Bohao Chang, Bo Hu, Yifan Zhou   +8 more
wiley   +1 more source

CXCR7 mediates angiogenesis in human glioma

, 2013
64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Guentchev, M, Tchorbanov, A, Birner, P, Tuettenberg, J   +3 more
openaire   +1 more source

グリオブラストーマ細胞の増殖に対するヒト間葉系幹細胞の作用機構解明 [PDF]

, 2013
筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences2012【要旨 ...
106106, 秋本, 恵子
core   +1 more source

Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors [PDF]

, 2018
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine receptors control distinct biological processes, and the same receptor can direct different cellular responses, but the basis ...
Malhotra, Divyanshu, Raz, Erez, Shin, Jimann, Solnica-Krezel, Lilianna   +3 more
core   +2 more sources

CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis.

PLoS ONE, 2018
The CXCR4/CXCL12 axis has been extensively associated with different types of cancer correlating with higher aggressiveness and metastasis. In diffuse large B-cell lymphoma (DLBCL), the expression of the chemokine receptor CXCR4 is involved in the ...
María José Moreno, Alberto Gallardo, Silvana Novelli, Ana Mozos, Marc Aragó, Miguel Ángel Pavón, María Virtudes Céspedes, Víctor Pallarès, Aïda Falgàs, Miguel Alcoceba, Oscar Blanco, Marcos Gonzalez-Díaz, Jorge Sierra, Ramon Mangues, Isolda Casanova   +14 more
doaj   +1 more source