Results 101 to 110 of about 6,662 (210)
CXCR7 regulates multiple functions in HBMECs.
, 2014 A. shRNA-scramble CXCR7 or shRNA-CXCR7 HBMECs were seeded on 96 well plate in the presence of 200 ng/ml CXCL12 and cell proliferation was analyzed by XTT assay as described in “Materials and Methods”. B.
Kevin A. Walter (607333) +2 more
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Stem Cell Research, 2017 CXCR4 and CXCR7 are prominent G protein-coupled receptors (GPCRs) for chemokine stromal cell-derived factor-1 (SDF-1/CXCL12). This study demonstrates that CXCR4 and CXCR7 induce differential effects during cardiac lineage differentiation and β-adrenergic
Delaine K. Ceholski +10 more
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Structural studies on the CXCR7 decoy receptor
EMBnet.journal, 2012 Motivations. Recent studies have revealed that the chemokine receptor CXCR7 plays an important role in cancer development. However, little is known about the effect of CXCR7 on the process of hepatocellular carcinoma (HCC) cell invasion and angiogenesis. In particular, CXCR7 was overexpressed in HCC tissues.
De Vero, T, Costantini, S, Colonna, G
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Macrophage CXCR7: A Potential New Target for Atherosclerosis
, 2013 Objective—The discovery of CXCR7 as a new receptor for SDF-1 places many previously described SDF-1 functions attributed to CXCR4 in question, though whether CXCR7 acts as a signaling or “decoy” receptor has been in debate.
Ma, Wanshu
core
Effect of CXCR7 receptor overexpression on U2932 DLBCL cells.
, 2018 (A) Quantification of CXCR7 expression by flow cytometry, in the total population of transfected U2932-CXCR7 and U2932-control cells or after measurements restricted only to GFP+ cells.
Miguel Alcoceba (3805117) +14 more
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CXCR4 immunoreactivity in CXCR7 deficient kidneys.
, 2012 (A,B) In situ hybridizations with a radiolabeled CXCR4 probe show similar CXCR4 expression patterns and labeling intensities in the E14.5 kidney of a wildtype and a CXCR7 deficient mutant.
Wiebke Mueller (144965) +8 more
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Expression and function of CXCL12/CXCR4/CXCR7 in thyroid cancer
International Journal of Oncology, 2016 The contribution of CXCL12/CXCR4/CXCR7 axis to cancer progression has been increasingly recognized. However, its role in thyroid cancer development remains unclear. The present study aimed to examine the expression and function of CXCL12 and its receptors in thyroid cancer.
ZHU, XIAOLI +6 more
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Histological analysis of CXCR7-deficient kidneys.
, 2012 Kidney sections of E16.5 wildtype (A–C) and CXCR7 deficient littermates (D–F) were stained with periodic acid-Schiff (PAS) reagents. (A,D) Macroscopic images demonstrate that the overall kidney morphology is normal in the CXCR7 knockout embryo. (B,C,E,F)
Wiebke Mueller (144965) +8 more
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Stimulation of TLR4 by LMW-HA Induces Metastasis in Human Papillary Thyroid Carcinoma through CXCR7
Clinical and Developmental Immunology, 2013 In inflammatory sites, high molecular weight hyaluronan fragments are degraded into lower molecular weight hyaluronan fragments (LMW-HA) to regulate immune responses. However, the function of LMW-HA in PTC progression remains to be elucidated.
Shipeng Dang +14 more
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A patent review of CXCR7 modulators (2019-present)
Expert Opinion on Therapeutic PatentsAtypical chemokine receptor 3 (ACKR3) (formerly CXCR7) regulates various biological processes through its ligands and is closely associated with numerous diseases, including inflammation, cancer, cardiovascular diseases (CVDs), pain, and neurological disorders.
Thanigaimalai Pillaiyar, Stefan Laufer
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