Results 41 to 50 of about 6,925 (209)
CXCR7 is highly expressed in acute lymphoblastic leukemia and potentiates CXCR4 response to CXCL12. [PDF]
PLoS ONE, 2014 Recently, a novel CXCL12-binding receptor, has been identified. This CXCL12-binding receptor commonly known as CXCR7 (CXC chemokine receptor 7), has lately, based on a novel nomenclature, has received the name ACKR3 (atypical chemokine receptor 3).
Rita de Cássia Carvalho Melo +7 more
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Endothelial CXCR7 regulates breast cancer metastasis [PDF]
Oncogene, 2015 Atypical chemokine receptor CXCR7 (ACKR3) functions as a scavenger receptor for chemokine CXCL12, a molecule that promotes multiple steps in tumor growth and metastasis in breast cancer and multiple other malignancies. Although normal vascular endothelium expresses low levels of CXCR7, marked upregulation of CXCR7 occurs in tumor vasculature in breast ...
Stacer, Amanda C. +8 more
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Cell & Bioscience, 2022 Background Chemokine CXC motif receptor 7 (CXCR7) is an atypical G protein-coupled receptor (GPCR) that signals in a biased fashion. CXCL12/CXCR7 biased signal has been reported to play crucial roles in multiple stages of colorectal cancer (CRC). However,
Mahan Si +7 more
doaj +1 more source
, 2014 A, Representative immunocytofluorescence image for CXCR7 (red) in HBMECs. Nuclei are stained with DAPI (blue). B, Flow cytometry analysis for CXCR7 in HBMECs.
Kevin A. Walter (607333) +2 more
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, 2018 (A) Patients bearing CXCR7+ tumors showed significantly higher OS than patients bearing CXCR7- tumors. (B) Patients bearing CXCR4+CXCR7+ tumors also showed significantly higher OS than patients bearing CXCR4+CXCR7- tumors.
Miguel Alcoceba (3805117) +14 more
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CENPF Promotes EMT in Non-small Cell Lung Cancer by Up-regulating ACKR3/CXCR7
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the relationship between the expression of CENPF in NSCLC adenocarcinoma (LUAD) and the clinical prognosis of patients and its effect on the metastasis of lung adenocarcinoma cells. Methods The expression of CENPF in LUAD and its
GU Tong +6 more
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CXCL12, CXCR4 and CXCR7 expression in brain metastases [PDF]
Cancer Biology & Therapy, 2009 Brain metastases occur in about 25% of patients who die of cancer. The most common sources of brain metastases in adults are lung, breast, kidney, colorectal cancer and melanoma. The chemokine/receptor system CXCL12/CXCR4 plays a key role in multiple biological functions; among these, homing of neoplastic cells from the primary site to the target and ...
Paola Gaviani +9 more
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Scientific Reports, 2017 The atypical C-X-C chemokine receptor 7 (CXCR7) has been implicated in supporting aggressive cancer phenotypes in several cancers including prostate cancer.
James J. Hoy +3 more
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CXCR7 has higher expressed in ALL.
, 2014 Quantitative expression of CXCR7 mRNA in patient cells relative to healthy donor cells and among different patient groups. Real time RT-PCR was performed on cDNA from the samples of patients with hematopoietic malignancies or from bone marrow samples ...
Mariana Ozello Baratti (517831) +7 more
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Frontiers in Oncology, 2021 The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors (GPCRs) activated through their shared ligand CXCL12 in multiple human cancers.
Sara Santagata +6 more
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