Results 61 to 70 of about 10,649 (214)

CXCR4/CXCR7/CXCL12-Axis in Follicular Thyroid Carcinoma [PDF]

Journal of Cancer, 2018
Background: Follicular thyroid carcinoma's (FTC) often benign course is partially due to adjuvant radioactive iodine (RAI) treatment. However, once the tumour has spread and fails to retain RAI, the therapeutic options are limited and the outcome is poor.
Werner, Thomas Artur, Forster, Christina Maria, Dizdar, Levent, Verde, Pablo Emilio, Raba, Katharina, Schott, Matthias, Knoefel, Wolfram Trudo, Krieg, Andreas   +7 more
openaire   +2 more sources

Macrophage migration inhibitory factor (MIF) family in arthropods : Cloning and expression analysis of two MIF and one D-dopachrome tautomerase (DDT) homologues in Mud crabs, Scylla paramamosain [PDF]

, 2016
Acknowledgements This research was supported by grants from the National Natural Science Foundation of China (Nos. 31172438 and U1205123), the Natural Science Foundation of Fujian Province (No.
Duan, Li-Peng, Huang, Bei, Huang, Wen-Shu, Jia, Qin-qin, Nie, Pin, Wang, Ke-Jian, Wang, Tiehui, Zhang, Cai-Liang   +7 more
core   +1 more source

CENPF Promotes EMT in Non-small Cell Lung Cancer by Up-regulating ACKR3/CXCR7

Zhongliu Fangzhi Yanjiu, 2022
Objective To investigate the relationship between the expression of CENPF in NSCLC adenocarcinoma (LUAD) and the clinical prognosis of patients and its effect on the metastasis of lung adenocarcinoma cells. Methods The expression of CENPF in LUAD and its
GU Tong, JIANG Yuheng, DING Shu, CHEN Wei, LUO Chao, YU Weiyong, CHEN Xiaofei   +6 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

CXCR7 protein expression in human adult brain and differentiated neurons. [PDF]

PLoS ONE, 2011
BACKGROUND:CXCR7 and CXCR4 are receptors for the chemokine CXCL12, which is involved in essential functions of the immune and nervous systems. Although CXCR7 transcripts are widely expressed throughout the central nervous system, little is known about ...
Saori Shimizu, Michael Brown, Rajarshi Sengupta, Mark E Penfold, Olimpia Meucci   +4 more
doaj   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

CXCR7 promotes melanoma tumorigenesis via Src kinase signaling [PDF]

Cell Death & Disease, 2019
AbstractChemokine receptors have been documented to exert critical functions in melanoma progression. However, current drugs targeting these receptors have limited efficacy in clinical applications, suggesting the urgency to further explore the roles of chemokine receptors in melanoma.
Shuai Xu, Jintian Tang, Wei Wang, Jie Liu, Yan Fu, Yongzhang Luo   +5 more
openaire   +2 more sources

Chemokines in the balance: Maintenance of homeostasis and protection at CNS barriers [PDF]

, 2014
In the adult central nervous system (CNS), chemokines and their receptors are involved in developmental, physiological and pathological processes. Although most lines of investigation focus on their ability to induce the migration of cells, recent ...
Holman, David W, Klein, Robyn S, Williams, Jessica L   +2 more
core   +3 more sources

CXCR7-mediated progression of osteosarcoma in the lungs [PDF]

British Journal of Cancer, 2013
Osteosarcoma (OS) is the most frequent primary malignant bone tumour in children and adolescents with a high propensity for lung metastasis. Chemokines and chemokine receptors have been described to have an important role in many malignancies including OS.
Goguet-Surmenian, E, Richard-Fiardo, P, Guillemot, E, Benchetrit, M, Gomez-Brouchet, A, Buzzo, P, Karimdjee-Soilihi, B, Alemanno, P, Michiels, J-F, Schmid-Alliana, A, Schmid-Antomarchi, H   +10 more
openaire   +2 more sources

Structure and functional motifs of GCR1, the only plant protein with a GPCR fold? [PDF]

, 2013
Whether GPCRs exist in plants is a fundamental biological question. Interest in deorphanizing new G protein coupled receptors (GPCRs), arises because of their importance in signaling.
Abdalla, Nuradin Y, Bailey, Gregory R, Jordon, Sian R D, Reeves, Philip J, Reynolds, Christopher A, Taddese, Bruck, Upton, Graham J G   +6 more
core   +1 more source