Results 61 to 70 of about 6,662 (210)
Stem Cell Research & Therapy, 2018 CXCR4 was the first receptor identified for CXCL12, but a second receptor, CXCR7, has also been described and its function in hematopoietic cells remains unknown.
Rita de Cassia Carvalho Melo +3 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.The progression of silicosis‐associated fibrosis relies on a positive feedback loop mediated by crosstalk between Cxcr4+ macrophages and Cxcl12+ fibroblasts and the therapeutic potential of targeting the Cxcl12/Cxcr4 axis with AMD3100 as a novel strategy for treating silicosis.
Min Mu +11 more
wiley +1 more source
5T4 is not required for CXCR7 surface expression.
, 2013 Immunofluorescence detection of 5T4 and CXCR7 in undifferentiated and differentiating WT and 5T4KO-ES cells (5T4 = green, CXCR7 = red). Cell surface expression of CXCR7 is high in undifferentiated ES cells (either WT or 5T4KO).
Christopher M. Ward (213849) +10 more
core +1 more source
Heliyon, 2018 Chemokine receptors CCR5 and CXCR4 are considered the main coreceptors for initial HIV infection, replication and transmission, and subsequent AIDS progression.
Thomas D'huys +3 more
doaj +1 more source
Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein. [PDF]
PLoS ONE, 2013 Angiogenesis is a critical factor in the growth and dissemination of solid tumors. Indeed, tumor vasculature is abnormal and contributes to the development and spread of malignancies by creating a hostile microenvironment.
Jennifer E Totonchy +4 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Juan Li +5 more
wiley +1 more source
, 2016 (A-F) CXCR7 staining revealed receptor expression on cells in control brains (B) and different regions of the MS brain including demyelinated (E; DM) and remyelinating (F; RM) lesions as well as active white matter lesions (D).
David Kremer (444311) +6 more
core +1 more source
Diagnostic Pathology, 2019 Background Lipopolysaccharide (LPS) from Helicobacter pylori (HP) plays an important role in gastric cancer occurrence and development. Toll-like receptor 4 (TLR4) and myeloid differential protein-2 (MD-2) are also reported to be involved in gastric ...
Nan Li +6 more
doaj +1 more source
Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells
Respiratory Research, 2020 Background Under physiological conditions, CXCL12 modulates cell proliferation, survival, angiogenesis, and migration mainly through CXCR4. Interestingly, the newly discovered receptor CXCR7 for CXCL12 is highly expressed in many tumor cells as well as ...
Huan Liu +8 more
doaj +1 more source
Etiopathogenesis of Immune‐Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances
CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.This review systematically clarifies that the core of IMNM begins with specific autoantibodies, which in turn trigger complement activation, immune cell infiltration, and a storm of inflammatory factors. Together, these processes induce regulatory cell death and mitochondrial dysfunction, ultimately leading to muscle fiber necrosis. Genetic factors and
Chang Gao +4 more
wiley +1 more source