Results 141 to 150 of about 40,137 (294)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy. [PDF]

J Virol, 2022
Jiang S, Xia N, Luo J, Zhang Y, Cao Q, Zhang J, Wang Y, Zhao Y, Zheng W, Chen N, Meurens F, Li X, Zhu J.   +12 more
europepmc   +1 more source

Mechanism of morphine in increasing plasma cyclic GMP level in male mice

, 1982
Takamura Muraki, Hiroya Uzumaki, Teruo Nakadate, Ryuichi Kato   +3 more
openalex   +1 more source

Cyclic‐di‐GMP‐mediated signalling within the σ^S network of Escherichia coli [PDF]

, 2006
Harald Weber, Christina Pesavento, Alexandra Possling, Gilbert Tischendorf, Regine Hengge   +4 more
openalex   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Double take: A dual-functional Hypr GGDEF synthesizes both cyclic di-GMP and cyclic GMP-AMP to control predation in Bdellovibrio bacteriovorus. [PDF]

PLoS Genet, 2022
Rangarajan AA, Waters CM.
europepmc   +1 more source

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

, 1982
James B. Hurley, Lubert Stryer
openalex   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP. [PDF]

Sci Adv
Ali M, Dura R, Guery MA, Colard-Itté E, Cheviet T, Robresco L, Berry L, Lionne C, Lavazec C, Claessens A, Peyrottes S, Wengelnik K, Wein S, Cerdan R.   +13 more
europepmc   +1 more source