Results 211 to 220 of about 72,449 (334)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Natriuretic peptide receptor B maintains heart rate and sinoatrial node function via cyclic GMP-mediated signalling. [PDF]

Cardiovasc Res, 2022
Dorey TW, Mackasey M, Jansen HJ, McRae MD, Bohne LJ, Liu Y, Belke DD, Atkinson L, Rose RA.   +8 more
europepmc   +1 more source

Effect of cyclic GMP derivative on K-stimulated 45Ca-uptake by crude synaptosomal fractions from rat brain

, 1979
Seiji Ichida, K Okada, Norifumi Yonehara, Tomohiro Matsuda, Hiroshi Yoshida   +4 more
openalex   +1 more source

Performance Evaluation of a New HRD Assay (HRDsig) in Ovarian Carcinomas in Australia

Journal of Clinical Laboratory Analysis, EarlyView.
In this study we have evaluated the performance of a new HRD assay (HRDsig) against two accredited HRD assays, as well as against commercial controls and inter‐laboratory comparison samples. HRDsig has demonstrated a high concordance rate for determining HRD status in ovarian carcinomas.
Pranav Dorwal, Liyan Song, Priscillia Siswara, Amit Kumar, Julie Robin, Noel Djitro, Anna Fong Na Goh, Ravikiran Vedururu, Bin Yuan, Ashleigh Levine, Suzanne Svobodova, Beena Kumar   +11 more
wiley   +1 more source

Regulation of calcium entry by cyclic GMP signaling in Toxoplasma gondii. [PDF]

J Biol Chem
Hortua Triana MA, Márquez-Nogueras KM, Fazli MS, Quinn S, Moreno SNJ.   +4 more
europepmc   +1 more source

Interference on Cytosolic DNA Activation Attenuates Sepsis Severity: Experiments on Cyclic GMP-AMP Synthase (cGAS) Deficient Mice. [PDF]

Int J Mol Sci, 2021
Visitchanakun P, Kaewduangduen W, Chareonsappakit A, Susantitaphong P, Pisitkun P, Ritprajak P, Townamchai N, Leelahavanichkul A.   +7 more
europepmc   +1 more source

Characterization of a calmodulin-dependent high-affinity cyclic AMP and cyclic GMP phosphodiesterase from male mouse germ cells [PDF]

, 1984
Raffaele Geremia, Pellegrino Rossi, David Mocini, R Pezzotti, Marco Conti   +4 more
openalex   +1 more source

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +1 more source

Brain endothelial cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway in aging and neurodegeneration. [PDF]

Neural Regen Res
Sun B, Li L, Luo J.
europepmc   +1 more source

Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase. [PDF]

PLoS Pathog, 2021
Sato H, Hoshi M, Ikeda F, Fujiyuki T, Yoneda M, Kai C.   +5 more
europepmc   +1 more source