The Heme-Based Oxygen-Sensor Phosphodiesterase Ec DOS (DosP): Structure-Function Relationships
Biosensors, 2013 Escherichia coli Direct Oxygen Sensor (Ec DOS, also known as Ec DosP) is a heme-based O2-sensing phosphodiesterase from Escherichia coli that catalyzes the conversion of cyclic-di-GMP to linear di-GMP.
Toru Shimizu
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Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. [PDF]
PLoS ONE, 2014 With the inevitable selection of resistance to antimalarial drugs in treated populations, there is a need for new medicines to enter the clinic and new targets to progress through the drug discovery pipeline.
Rita Tewari +4 more
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Cellular levels and binding of c-di-GMP control subcellular localization and activity of the Vibrio cholerae transcriptional regulator VpsT. [PDF]
PLoS Pathogens, 2012 The second messenger, cyclic diguanylate (c-di-GMP), regulates diverse cellular processes in bacteria. C-di-GMP is produced by diguanylate cyclases (DGCs), degraded by phosphodiesterases (PDEs), and receptors couple c-di-GMP production to cellular ...
Nicholas J Shikuma +2 more
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arXiv, 2014 Gabor filters can extract multi-orientation and multiscale features from face images. Researchers have designed different ways to use the magnitude of the filtered results for face recognition: Gabor Fisher classifier exploited only the magnitude information of Gabor magnitude pictures (GMPs); Local Gabor Binary Pattern uses only the gradient ...
arxiv
GMP-selected dual and lensed AGNs: selection function and classification based on near-IR colors and resolved spectra from VLT/ERIS, KECK/OSIRIS, and LBT/LUCI [PDF]
arXiv, 2023 The Gaia-Multi-Peak (GMP) technique can be used to identify large numbers of dual or lensed AGN candidates at sub-arcsec separation, allowing us to study both multiple SMBHs in the same galaxy and rare, compact lensed systems. The observed samples can be used to test the predictions of the models of SMBH merging once 1) the selection function of the ...
arxiv
Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch
Molecules, 2012 C-di-GMP, a cyclic guanine dinucleotide, has been shown to regulate biofilm formation as well as virulence gene expression in a variety of bacteria. Analogues of c-di-GMP have the potential to be used as chemical probes to study c-di-GMP signaling and ...
Herman O. Sintim +4 more
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Journal of Pharmacological Sciences, 2010 The present study was designed to identify the inhibitory neurotransmitters mediating nonadrenergic noncholinergic relaxation in the longitudinal muscle of C57/BL mouse distal colon.
Ayako Hidaka +3 more
doaj
mBio, 2010 The signaling nucleotide cyclic diguanylate (c-di-GMP) regulates the transition between motile and sessile growth in a wide range of bacteria. Understanding how microbes control c-di-GMP metabolism to activate specific pathways is complicated by the ...
Judith H. Merritt +7 more
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Molecules, 2018 Combination chemotherapy is a common clinical practice in cancer treatment. Here, cyclic RGD (arginylglycylaspartic acid) peptide was introduced to the surface of lipid/calcium/phosphate (LCP) asymmetric lipid layer nanoparticles for the co-delivery of ...
Jing Zhang +7 more
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Static structure factor and the dispersion of the Girvin-MacDonald-Platzman density mode for fractional quantum Hall fluids on the Haldane sphere [PDF]
PhysRevB.111.115132 (2025)We study the neutral excitations in the bulk of the fractional quantum Hall (FQH) fluids generated by acting with the Girvin-MacDonald-Platzman (GMP) density operator on the uniform ground state. Creating these density modulations atop the ground state costs energy, since any density fluctuation in the FQH system has a gap stemming from underlying ...
arxiv +1 more source