Results 41 to 50 of about 1,721,329 (334)

A macrolactonization approach to the total synthesis of the antimicrobial cyclic depsipeptide LI-F04a and diastereoisomeric analogues

Beilstein Journal of Organic Chemistry, 2012
The cyclic peptide core of the antifungal and antibiotic cyclic depsipeptide LI-F04a was synthesised by using a modified Yamaguchi macrolactonization approach.
James R. Cochrane, Dong Hee Yoon, Christopher S. P. McErlean, Katrina A. Jolliffe   +3 more
doaj   +1 more source

Supramolecular switching of the self-assembly of cyclic peptide-polymer conjugates via host-guest chemistry.

Chemical Communications, 2019
A supramolecular strategy of switching the self-assembly of cyclic peptide-polymer conjugates using host-guest chemistry is proposed. The formation of tubular supramolecular polymers based on cyclic peptide-polymer conjugates can be controlled by ...
Qiao Song, Jie Yang, Julia Y. Rho, S. Perrier   +3 more
semanticscholar   +1 more source

Methionine epimerization in cyclic peptides

RSC Advances, 2021
One step regioselective methionine epimerization in cyclic peptides followed by selective functionalization leads to chemical novelty.
Pramodkumar D. Jadhav, Jianheng Shen, Peta-Gaye Burnett, Jian Yang, Ramaswami Sammynaiken, Martin J. T. Reaney   +5 more
openaire   +3 more sources

Development of a Cyclic Peptide Inhibitor of the p6/UEV Protein-Protein Interaction.

ACS Chemical Biology, 2019
The budding of HIV from infected cells is driven by the protein-protein interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein.
Katherine Lennard, Reece M Gardner, Cyrielle Doigneaux, Francisco Castillo, A. Tavassoli   +4 more
semanticscholar   +1 more source

Natural Cyclic Peptides as an Attractive Modality for Therapeutics: A Mini Review

Molecules, 2018
Peptides are important biomolecules which facilitate the understanding of complex biological processes, which in turn could be serendipitous biological targets for future drugs. They are classified as a unique therapeutic niche and will play an important
Muna Ali Abdalla, Lyndy J. McGaw
doaj   +1 more source

Rational design of glycosaminoglycan binding cyclic peptides using cPEPmatch

Computational and Structural Biotechnology Journal
Cyclic peptides present a robust platform for drug design, offering high specificity and stability due to their conformationally constrained structures.
Brianda L. Santini, Margrethe Gaardløs, Dariusz Wyrzykowski, Sven Rothemund, Anja Penk, Martin Zacharias, Sergey A. Samsonov   +6 more
doaj   +1 more source

Presence of short and cyclic peptides in Acacia and Ziziphus honeys may potentiate their medicinal values

Open Chemistry, 2021
Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples.
ALaerjani Wed Mohammed Ali, Abu-Melha Saraa Abdullah, Khan Khalid Ali, Ghramh Hamed A., Alalmie Ali Yahya A., Alshareef Rahaf Mohammed Hussein, AL-Shehri Badria M., Mohammed Mohammed Elimam Ahamed   +7 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Identification of a Glypican-3 Binding Peptide From a Phage-Displayed Peptide Library for PET Imaging of Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Tumor-targeting peptides functioned as molecular probes are essential for multi-modality imaging and molecular-targeting therapy in caner theronostics.
Jiayao Yan, Jiayao Yan, Xiaoxiao Yu, Xiaoxiao Yu, Xiaotong Chen, Fangcen Liu, Fangjun Chen, Naiqing Ding, Lixia Yu, Fanyan Meng, Jie Shen, Jia Wei, Baorui Liu, Baorui Liu, Baorui Liu   +14 more
doaj   +1 more source

Janus cyclic peptide–polymer nanotubes [PDF]

Nature Communications, 2013
Self-assembled nanotubular structures have numerous potential applications but these are limited by a lack of control over size and functionality. Controlling these features at the molecular level may allow realization of the potential of such structures.
Maarten, Danial, Carmen My-Nhi, Tran, Philip G, Young, Sébastien, Perrier, Katrina A, Jolliffe   +4 more
openaire   +2 more sources