Results 11 to 20 of about 424,248 (339)

Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction [PDF]

The EMBO Journal, 2000
The key regulator of G(2)-M transition of the cell cycle is M-phase promoting factor (MPF), a complex composed of cdc2 and a B-type cyclin. Cyclin B1 nuclear localization involves phosphorylation within a region called the cytoplasmic retention signal, which also contains a nuclear export signal.
Kong, Monica, Barnes, Elizabeth A, Ollendorff, Vincent, Donoghue, Daniel J.   +3 more
openaire   +4 more sources

A Journey through Time on the Discovery of Cell Cycle Regulation

Cells, 2022
All living organisms on Earth are made up of cells, which are the functional unit of life. Eukaryotic organisms can consist of a single cell (unicellular) or a group of either identical or different cells (multicellular).
Rustem Uzbekov, Claude Prigent
doaj   +1 more source

The Antiproliferation Activity of Ganoderma formosanum Extracts on Prostate Cancer Cells

Mycobiology, 2020
Androgen-independent prostate cancer accounts for mortality in the world. In this study, various extracts of a medical fungus dubbed Ganoderma formosanum were screened for inhibition of DU145 cells, an androgen-independent prostate cancer cell line ...
Cheng-Yen Chiang, Kai-Di Hsu, Yen-Yi Lin, Chang-Wei Hsieh, Jui-Ming Liu, Tze-Ying Lu, Kuan-Chen Cheng   +6 more
doaj   +1 more source

New Propargyloxy Derivatives of Galangin, Kaempferol and Fisetin—Synthesis, Spectroscopic Analysis and In Vitro Anticancer Activity on Head and Neck Cancer Cells

Cells, 2023
Head and neck cancer (HNC) therapy is limited; therefore, new solutions are increasingly being sought among flavonoids, which exhibit numerous biological properties, including potential anticancer activity.
Robert Kubina, Kamil Krzykawski, Arkadiusz Sokal, Marcel Madej, Arkadiusz Dziedzic, Monika Kadela-Tomanek   +5 more
doaj   +1 more source

Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13

Frontiers in Cell and Developmental Biology, 2019
Congenital heart defects, dysmorphic facial features and intellectual developmental disorders (CHDFIDD) syndrome in humans was recently associated with mutation in CDK13 gene.
Monika Nováková, Marek Hampl, Marek Hampl, Dávid Vrábel, Jan Procházka, Jan Procházka, Silvia Petrezselyová, Silvia Petrezselyová, Michaela Procházková, Michaela Procházková, Radislav Sedláček, Radislav Sedláček, Michaela Kavková, Tomáš Zikmund, Jozef Kaiser, Hsien-Chia Juan, Ming-Ji Fann, Marcela Buchtová, Marcela Buchtová, Jiří Kohoutek   +19 more
doaj   +1 more source

Venezuelan Equine Encephalitis Virus Capsid Implicated in Infection-Induced Cell Cycle Delay in vitro

Frontiers in Microbiology, 2018
Venezuelan equine encephalitis virus (VEEV) is a positive sense, single-stranded RNA virus and member of the New World alphaviruses. It causes a biphasic febrile illness that can be accompanied by central nervous system involvement and moderate morbidity
Lindsay Lundberg, Jacque Fontenot, Shih-Chao Lin, Chelsea Pinkham, Brian D. Carey, Catherine E. Campbell, Kylene Kehn-Hall   +6 more
doaj   +1 more source

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro [PDF]

, 2010
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs).
Ainscough, Berezney, Brown, Cardoso, Chevalier, Cook, Coverley, Coverley, den Hollander, Dijkwel, Djeliova, Fujita, Furstenthal, Geng, Geng, Harper, Hozak, Krude, Lowe, Mailand, Mitsui, Moore, Parisi, Radichev, Sherr, Stoeber, Su, Takeda, Tatsumi, Wilmes, Wohlschlegel   +30 more
core   +3 more sources

Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b) [PDF]

, 2009
Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870).
Benavides, Fernando, Blando, Jorge, Cardenas, Kim, Conti, Claudio, Johnson, David G., Knudsen, Erik S., Pérez, Carlos, Richie, Ellen, Rodriguez Puebla, Marcelo L., Rojas, Paola Andrea, Senderowicz, Adrian M.   +10 more
core   +1 more source

Cell Cycle Regulation in the Plant Response to Stress

Frontiers in Plant Science, 2020
As sessile organisms, plants face a variety of environmental challenges. Their reproduction and survival depend on their ability to adapt to these stressors, which include water, heat stress, high salinity, and pathogen infection.
Feifei Qi, Fuxin Zhang
doaj   +1 more source

Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy

Open Biology, 2022
Measuring the dynamics with which the regulatory complexes assemble and disassemble is a crucial barrier to our understanding of how the cell cycle is controlled that until now has been difficult to address.
Martina Barbiero, Luca Cirillo, Sapthaswaran Veerapathiran, Catherine Coates, Camilla Ruffilli, Jonathon Pines   +5 more
doaj   +1 more source