Results 101 to 110 of about 50,064 (212)

Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? [PDF]

, 2014
The molecular chaperone heat shock protein 90 alpha (Hsp90α) has been recognized in various tumours including glioma. This pilot study using a proteomic approach analyses the downstream effects of Hsp90 inhibition using 17-allylamino-17 ...
Khan, Zarine Jamsher, Munje, Chinmay, Shervington, Amal A, Shervington, Leroy Alexander   +3 more
core   +2 more sources

Serum Angptl2 and CyPA Levels in Acute Myocardial Infarction and In-Stent Restenosis After Percutaneous Coronary Intervention: A Single-Center Retrospective Case-Control Study

Vascular Health and Risk Management
Pimo Zhou, Tai Yang, Hua Huang, Fang Tang, Peng Jin, Bo Zhou Department of Cardiovascular Medicine, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie City, Guizhou Province, People’s Republic of ChinaCorrespondence: Bo Zhou, Department of ...
Zhou P, Yang T, Huang H, Tang F, Jin P, Zhou B   +5 more
doaj  

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

eLife, 2017
RIG-I is a key cytosolic pattern recognition receptor that interacts with MAVS to induce type I interferons (IFNs) against RNA virus infection. In this study, we found that cyclophilin A (CypA), a peptidyl-prolyl cis/trans isomerase, functioned as a ...
Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun   +14 more
doaj   +1 more source

Cyclophilin A in Cardiovascular Homeostasis and Diseases

The Tohoku Journal of Experimental Medicine, 2015
Vascular homeostasis is regulated by complex interactions between many vascular cell components, including endothelial cells, vascular smooth muscle cells (VSMCs), adventitial inflammatory cells, and autonomic nervous system. The balance between oxidant and antioxidant systems determines intracellular redox status, and their imbalance can cause ...
openaire   +3 more sources

Progress of CypA and Lung Cancer-related Research

Chinese Journal of Lung Cancer, 2010
CypA is the most important member of Cyclophilins. It is a widely expressed protein in nature possessing PPIase and chaperone activities which help the precise folding of protein. Also, it is involved in immunosuppression, inflammation and the balance of
Zhe QIAN, Wentao YUE, Baolan LI
doaj  

Crystal structures of wild-type and mutated cyclophilin B that causes hyperelastosis cutis in the American quarter horse

BMC Research Notes, 2012
Background Hyperelastosis cutis is an inherited autosomal recessive connective tissue disorder. Affected horses are characterized by hyperextensible skin, scarring, and severe lesions along the back. The disorder is caused by a mutation in cyclophilin B.
Boudko Sergei P, Ishikawa Yoshihiro, Lerch Thomas F, Nix Jay, Chapman Michael S, Bächinger Hans   +5 more
doaj   +1 more source

Diagnostic Value of Cyclophilin A in Acute Ischemic Stroke

Eurasian Journal of Emergency Medicine, 2017
Aim: The early diagnosis and treatment of patients presenting to the emergency department symptoms of stroke can significantly reduce mortality and morbidity rates associated with it.
Yunus Karaca, Özgür Tatlı, Umut Eryiğit, Nurhak Aksüt, Aynur Şahin, Ahmet Menteşe, Diler Us Altay, Necla Beşlioğlu, Mevlüt Karataş, Asım Örem   +9 more
doaj   +1 more source

Intracellular Ca 2+ sensing: role in calcium homeostasis and signaling [PDF]

, 2017
Ca2+ is a ubiquitous intracellular messenger that controls diverse cellular functions but can become toxic and cause cell death. Selective control of specific targets depends on spatiotemporal patterning of the calcium signal and decoding it by multiple,
Bagur, Rafaela, Hajnóczky, György
core   +1 more source

Dialysate cyclophilin A as a predictive marker for historical peritonitis in patients undergoing peritoneal dialysis

Heliyon
Introduction: No markers have been used to diagnose historical peritoneal dialysis (PD)-related peritonitis. Cyclophilin A (CypA) is associated with glucose toxicity and inflammation.
Shang-Feng Tsai, Cheng-Hsu Chen, Ming-Ju Wu, Mingli Hsieh   +3 more
doaj   +1 more source

Radial Spoke Proteins of \u3cem\u3eChlamydomonas\u3c/em\u3e Flagella [PDF]

, 2006
The radial spoke is a ubiquitous component of `9+2\u27 cilia and flagella, and plays an essential role in the control of dynein arm activity by relaying signals from the central pair of microtubules to the arms. The Chlamydomonas reinhardtii radial spoke
Agrin, Nathan S., Diener, Dennis R., Dienes, Jennifer M., Kamiya, Ritsu, King, Stephen M., Kohno, Takahiro, Pazour, Gregory J., Rosenbaum, Joel L., Sale, Winfield S., Witman, George B., Yang, Chun, Yang, Pinfen   +11 more
core   +1 more source