Results 131 to 140 of about 45,384 (211)
Cymbimicin A and B, Two Novel Cyclophilin-binding Structures Isolated from Actinomycetes.
The Journal of Antibiotics, 1997 Two novel metabolites, cymbimicins A and B, were isolated from the culture broth of a strain of Micromonospora sp. by screening for cyclophilin binding metabolites from actinomycete strains. Cymbimicin A binds to cyclophilin A with a high affinity six fold lower than to that of cyclosporin A.
T, Fehr +10 more
openaire +3 more sources
Time-Resolved Metabolomics Reveals Mitochondrial Protection in Septic Liver Injury
MetabolitesBackground/Objectives: Sepsis is a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection. Mitochondrial dysfunction is considered a key contributor to the pathogenesis of sepsis, but its molecular ...
Naoki Suzuki +4 more
doaj +1 more source
Intracellular Ca 2+ sensing: role in calcium homeostasis and signaling [PDF]
, 2017 Ca2+ is a ubiquitous intracellular messenger that controls diverse cellular functions but can become toxic and cause cell death. Selective control of specific targets depends on spatiotemporal patterning of the calcium signal and decoding it by multiple,
Bagur, Rafaela, Hajnóczky, György
core +1 more source
Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections
VirusesCyclophilin (Cyp) inhibitors are of clinical interest in respect to their antiviral activities in the context of many viral infections including chronic hepatitis B and C.
Jennifer Molle +6 more
doaj +1 more source
Radial Spoke Proteins of \u3cem\u3eChlamydomonas\u3c/em\u3e Flagella [PDF]
, 2006 The radial spoke is a ubiquitous component of `9+2\u27 cilia and flagella, and plays an essential role in the control of dynein arm activity by relaying signals from the central pair of microtubules to the arms. The Chlamydomonas reinhardtii radial spoke
Agrin, Nathan S. +11 more
core +1 more source
Cyclophilin B overexpression predicts a poor prognosis and activates metastatic pathways in colon cancer. [PDF]
Transl Cancer Res, 2020 Zhang X, Tan J, Yang L, An G.
europepmc +1 more source
Inorganic polyphosphate controls cyclophilin B-mediated collagen folding in osteoblast-like cells. [PDF]
FEBS J, 2020 Khong ML +4 more
europepmc +1 more source
APRIL:TACI axis is dispensable for the immune response to rabies vaccination. [PDF]
, 2017 There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings.
Alugupalli, Kishore R. +5 more
core +1 more source