Results 51 to 60 of about 5,651 (185)
Nature Communications, 2017 Chiral spirocyclic compounds are important structural motifs for drug discovery. Here, the authors report a synthetic route to spirocycles based on enantioselective cycloaddition of activated spirocyclopropyl oxindoles, which act as donor-acceptor ...
Peng-Wei Xu +6 more
doaj +1 more source
Light‐Induced Reactions of Small‐Membered Cyclic Carbonyl Compounds
European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.This review highlights recent advances in the synthesis and photochemical reactivity of cyclopropenone and cyclobutenedione. These compounds undergo photolysis upon direct excitation, and in some cases, through indirect excitation by photocatalysts. The resulting photogenerated species exhibit unique reactivity profiles that are strongly influenced by ...
Kenji Mishiro
wiley +1 more source
A unique Pd-catalysed Heck arylation as a remote trigger for cyclopropane selective ring-opening
Nature Communications, 2017 Functionalizing multiple, distant sites across a molecule is a challenge. Here the authors report a remote functionalization strategy, whereby an initial Heck reaction leads to chain-walking of palladium across a molecule, ring-opening cyclopropanes ...
Sukhdev Singh +3 more
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Synthesis of organic liquid crystals containing selectively fluorinated cyclopropanes
Beilstein Journal of Organic Chemistry, 2020 This paper describes the synthesis of a series of organic liquid crystals (LCs) containing selectively fluorinated cyclopropanes at their termini. The syntheses used difluorocarbene additions to olefin precursors, an approach which proved straightforward
Zeguo Fang +5 more
doaj +1 more source
Alpha‐Ester Aryl Diazirines: Low‐Temperature Carbene Progenitors for Materials Applications
Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.A synthetic route to α‐ester aryl diazirines is established. The products are shown to have low activation temperatures, and to form stabilized singlet carbenes, resulting in high‐yielding C–H insertion to unactivated aliphatic bonds. Applications in materials science and tissue adhesion are proposed.
Kate Andersen +6 more
wiley +1 more source
Advanced Science(Difluoromethylated cyclopropane represents an important motif, which is widely found in bioactive and functional molecules. Despite significant progress in modern chemistry, the atom‐economic and enantioselective synthesis of difluoromethylated ...
Chuntao Wang +3 more
doaj +1 more source
Nature Communications, 2018 Synthesis of cyclopropanes bearing vicinal all-carbon quaternary stereocenters poses synthetic challenges. Here, the authors report an intramolecular radical cyclopropanation with a copper/amine cooperative catalytic system for the efficient construction
Liu Ye +5 more
doaj +1 more source
Nature Communications, 2016 Furans are attractive staring materials in organic chemistry, due to the ease of functionalisation and sourcing from renewable feedstocks. Here the authors show the ring opening of furans to silane intermediates, followed by further conversion to ...
Chinmoy K. Hazra +3 more
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Asymmetric one-pot synthesis of cyclopropanes
Macedonian Journal of Chemistry and Chemical Engineering, 2016 Cycloaddition of the diazoalkanes to electron-deficient olefins (in situ) affords polysubstituted cyclopropanes in high yields (up to 85%). Deprotection of the ketal protecting group provided water-soluble cyclopropane-bearing carbohydrate in good yields.
Naoufel Ben Hamadi +2 more
doaj +1 more source
Iodine-catalyzed diazo activation to access radical reactivity
Nature Communications, 2018 Radical reactivity of diazo compounds, useful organic building blocks, is yet underexplored. Here, the authors report an iodine-catalyzed radical activation of diazo compounds affording a variety of substituted cyclopropanes, pyrroles and epoxides under ...
Pan Li +5 more
doaj +1 more source