Results 191 to 200 of about 44,894 (310)

Изучение активности CYP2D6 по оценке фармакокинетики амитриптилина у носителей аллельного варианта CYP2D6*4

, 2008
Савельева М.И., Сычев Д.А. Proceedings of the III Congress of Pharmacology Russia, Saint-Petersburg, 23–27 September 2007. Abstr 569. Psychopharmacol Biol Narcol 2007 Sept; 7 Suppl (Pt 2, M–Ja): 2-1931–2-1931 [in Russian]Савельева М.И.,
Д. А. Сычев; Московская медицинская академия им. И.М. Сеченова Росздрава; Яузская ул., 11, корп. 4, Москва, 109240; ГКБ № 23 им. «Медсантруд», М. И. Савельева; Московская медицинская академия им. И.М. Сеченова Росздрава; Яузская ул., 11, корп. 4, Москва, 109240; ГКБ № 23 им. «Медсантруд»   +1 more
core   +1 more source

Phytochemical Profiling and Antibacterial Activity of Moroccan Monofloral Honeys Against Multidrug‐Resistant Uropathogens: In Vitro, ADMET, Molecular Docking, and Molecular Dynamics Approaches

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Multidrug‐resistant bacteria infections require alternative antimicrobial strategies. This study evaluated the phenolic composition, antibacterial activity, and in silico properties of four Moroccan monofloral honeys. Carob honey showed the greatest phenolic diversity, whereas citrus honey contained the lowest polyphenolic content.
Mourad Chikhaoui, Aziz Galman, Ahmed Chetoui, Oussama Khibech, Mohamed Reda Kachmar, Toufik Bouddine, Mohamed Bouhrim, Fahd A. Nasr, Mohammed Al‐Zharani, Ashraf Ahmed Qurtam, Rachid Lotfi, Houda El Hajjouji   +11 more
wiley   +1 more source

Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.
ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley   +1 more source

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1151-1171, September 2026.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho, Suvarna Khadilkar, Hema Divakar, Chiara Benedetto, Andrea R. Genazzani, Diana Ramos, Elizabete Argale, Enrique Herrera, Martha Hickey   +8 more
wiley   +1 more source

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene. [PDF]

Pharmacogenomics J
Tesfamicael KG, Musker M, Adelson DL, Lewis MD.   +3 more
europepmc   +1 more source

CYP2D6 Gene [PDF]

, 2020
openaire   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source

Roadmap for Mental Health Treatment Utilizing Pharmacogenomic Testing: Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
Allison P. Swanson, Emily K. Mewborn, Garyung Bae   +2 more
wiley   +1 more source

Clinician Perspectives on Prescribing Restrictions and Opioid Pain Management in Australian Podiatric Practice: A Qualitative Study

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Background Australian‐endorsed general podiatrists and podiatric surgeons (EGPs and EPSs, respectively) operate under a fixed prescribing formulary, the National Podiatry Scheduled Medicines List (NPSML), that restricts access to opioid analgesics including tramadol and tapentadol, despite emerging evidence questioning the efficacy of ...
Lachlan Aquilina, Mischa Kronenberg, Estie Kruger, Marc Tennant, Joon Soo Park   +4 more
wiley   +1 more source

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response. [PDF]

Pharmacogenomics J
Petković Ćurčin A, Jeremić A, Joković D, Šupić G, Simić K, Milosavljević F, Stojanović Z, Jukić MM.   +7 more
europepmc   +1 more source