Results 111 to 120 of about 2,697 (198)

Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina [PDF]

, 2011
Background Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological hallmarks including β-amyloid (Aβ) accumulation, oxidative stress, and apoptotic cell death.
Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh, Othman Ghribi   +4 more
core   +2 more sources

Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease [PDF]

, 2014
Alzheimer's disease (AD) and Niemann-Pick type C (NPC) disease are progressive neurodegenerative diseases with very different epidemiology and etiology.
Hećimović, Silva, Malnar, Martina, Mattsson, Niklas, Zetterberg, Henrik   +3 more
core   +1 more source

Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature [PDF]

, 2014
BACKGROUND: Aging is accompanied by increasing vulnerability to pathologies such as atherosclerosis (ATH) and Alzheimer disease (AD). Are these different pathologies, or different presentations with a similar underlying pathoetiology?
Alexandra Sapronova, Richard Lathe, Yuri Kotelevtsev   +2 more
core   +1 more source

Toward common mechanisms for risk factors in Alzheimer's syndrome [PDF]

, 2017
The global strategic goal of reducing health care cost, especially the prospects for massive increases due to expanding markets for health care services demanded by aging populations and/or people with a wide range of chronic disorders-disabilities, is a
Avila, J, Cedazo-Minguez, A, Khachaturian, ZS, Medina, M, Rossor, M   +4 more
core   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,, Alexander, Stephen Ph, Davies, Jamie A, Fabbro, Doriano, Faccenda, Elena, Harding, Simon D, Kelly, Eamonn, Marrion, Neil V, Pawson, Adam J, Peters, John A, Sharman, Joanna L, Southan, Christopher   +11 more
core   +15 more sources

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease

Neurobiology of Disease, 2005
Recent epidemiological, biological and genetic data indicate a relationship between cholesterol and Alzheimer's disease (AD) including the association of polymorphisms of ABCA1 (a gene that is known to participate in cholesterol and phospholipid ...
Sandrine Macé, Emmanuelle Cousin, Sylvain Ricard, Emmanuelle Génin, Emmanuel Spanakis, Carole Lafargue-Soubigou, Bérengère Génin, Raphaël Fournel, Sandrine Roche, Gilles Haussy, Florence Massey, Stéphane Soubigou, Georges Bréfort, Patrick Benoit, Alexis Brice, Dominique Campion, Melvyn Hollis, Laurent Pradier, Jésus Benavides, Jean-François Deleuze   +19 more
doaj   +1 more source

Lipidomics in Health and Diseases - Beyond the Analysis of Lipids [PDF]

, 2014
published_or_final_versio
Fan, P, Li, M, Wang, Y
core   +1 more source

Cholesterol 25-hydroxylation activity of CYP3A

Journal of Lipid Research, 2011
To date, many studies have been conducted using 25-hydroxycholesterol, which is a potent regulator of lipid metabolism. However, the origins of this oxysterol have not been entirely elucidated. Cholesterol 25-hydroxylase is one of the enzymes responsible
Akira Honda, Teruo Miyazaki, Tadashi Ikegami, Junichi Iwamoto, Tomomi Maeda, Takeshi Hirayama, Yoshifumi Saito, Tamio Teramoto, Yasushi Matsuzaki   +8 more
doaj   +1 more source

Studies on the Transcriptional Regulation of Cholesterol 24-Hydroxylase (CYP46A1) [PDF]

Journal of Biological Chemistry, 2006
Yoshihiko Ohyama, Steve Meaney, Maura Heverin, Lena Ekström, Anat Brafman, Millicent Shafir, Ulla Andersson, Maria Olin, Gösta Eggertsen, Ulf Diczfalusy, Elena Feinstein, Ingemar Björkhem   +11 more
openaire   +1 more source

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence [PDF]

, 2016
Additional file 3: Figure S3. Regulation of genes of Arrhythmogenic right ventricular cardiomyopathy pathway during senescence induction in HFF strains Genes of the “Arrhythmogenic right ventricular cardiomyopathy” pathway which are significantly up ...
A Chicas, A Ciccia, A Iglesias-Ara, A Kaneda, A Leonardo Di, A Massoud, A Musio, A Ors, A Poehlmann, A Saadane, A Smogorzewska, A Ventura, A Zuryń, A Zuryń, AA Goodarzi, AB Parrish, AC Baege, AC Johansson, AJ Nakamura, AJT Millis, AM Havelka, AY Maslov, B Cen, B Pandit, B Zhivotovsky, BD Chang, Bernardes Jesus de, BP Kaistha, C Kenyon, C Michaloglou, C Morvan Le, C Rouault, C Sandhu, C Sidler, C Trapnell, CF Winter de, Christoph Kaether, CM Aliouat-Denis, D Bhaumik, D Coppola, D Lodygin, D Muthna, DA Alcorta, DH Lackner, DH Larsen, DJ Baker, DM Finucane, DN Shelton, DR Bentley, DR Wonsey, DW Chan, E Hara, E Natarajan, E Pazolli, EJ Gavin, ES Hwang, F Debacq-Chainiaux, F d’Adda di Fagagna, F Ling, F Rapaport, F Rodier, F Rodier, F Seyednasrollah, FA Mallette, G Thuret, GP Dimri, GP Dimri, GP Dimri, H Harada, H Takai, H Zalzali, HJ Kim, HJ Kim, I Androic, I Ben-Porath, I Ben-Porath, I Wierstra, IB Roninson, IK Yoon, IM Kim, IP Kovalchuk, J Bartkova, J Bunt, J Campisi, J Campisi, J Campisi, J Campisi, J Laoukili, J Manns, J Pawlowski, J Tomida, J Zhao, JC Acosta, JC Jeyapalan, JF Passos, JH Chen, JH Chen, JH Chin, JM Dhahbi, JM Yi, JP Carey, JP Coppé, JR Smith, JW Hofmann, JW Shay, K Itahana, K Johung, K Suzuki, K Voutetakis, KH Choi, KS Kim, L Gopinathan, L Hayflick, L Hirsch, L Jia, L Meng, L Zhang, M Blank, M Braig, M Collado, M Kronschnabl, M Narita, M Petric, M Purcell, M Serrano, MA Bonelli, Marco Groth, Matthias Platzer, MD Robinson, MI Love, MJ Smout, MK Ha, MK Kang, MT Paulsen, N Kikuchi, N Martin, N Ohtani, N Wajapeyee, NF Mathon, NG Berube, O Aksoy, O Toussaint, P Dekker, P Flicek, P Gupta, P Luo, P Sun, Peter Hemmerich, Q Gan, QF Wu, R Binet, R Mirzayans, R Mjelle, R Salama, RA Quadri, Reinhard Guthke, RJ Sabin, RT Abraham, S Anders, S Courtois-Cox, S Ferrando-Martinez, S Gonzalez, S Haupt, S Honda, S Hubackova, S Kim, S Lin, S Marthandan, S Marthandan, S Marthandan, S Marthandan, S Pollok, S Ressler, S Schäuble, S Sivakumar, S Vaughan, S Walter, Shiva Marthandan, SJ Robles, SP Linke, SP Mooijaart, SS Myatt, Steffen Priebe, Stephan Diekmann, T Chen, T Kaneko, T Kidokoro, T Kuilman, TC Kuilman, TV Kalin, U Herbig, Uwe Menzel, V Gire, VV Kalinichenko, W Cosme-Blanco, W Luo, W Wagner, W Xue, XW Cheng, Y Bai, Y Benjamini, Y Chien, Y Kong, Y Kotake, Y Ma, Y Nakayama, Y Takahashi, Y Tan, Y Zhang, YH Hsu, YJ Choi, YM Kim, Z Chen, Z Gong, Z Wang, Z Xie   +215 more
core   +5 more sources