Results 101 to 110 of about 2,010 (126)

Image_2_Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1.PDF

, 2018
Intrauterine growth restriction (IUGR) and consumption of a high saturated fat diet (HFD) increase the risk of hypercholesterolemia, a leading cause of morbidity and mortality.
Amnon Schlegel (378366), Baifeng Yu (5306669), Erin K. Zinkhan (5306672)   +2 more
core   +1 more source

Identification of tryptophan metabolism-related biomarkers for nonalcoholic fatty liver disease through network analysis

Endocrine Connections
Background: Increasing evidence demonstrates that tryptophan metabolism is closely related to the development of nonalcoholic fatty liver disease (NAFLD). This study aimed to identify specific biomarkers of NAFLD associated with tryptophan metabolism and
Cuihua Jiang, Jianqi Liang, Kaibo Hu, Yanqing Ye, Jiajia Yang, Xiaozhi Zhang, Guilin Ye, Jing Zhang, Deju Zhang, Bin Zhong, Peng Yu, Liefeng Wang, Bin Zeng   +12 more
doaj   +1 more source

Branched-chain amino acids promote hepatic Cyp7a1 expression and bile acid synthesis via suppressing FGF21-ERK pathway

Branched-chain amino acids (BCAAs) including leucine, isoleucine and valine have been linked with metabolic and cardiovascular diseases. BCAAs homeostasis is tightly controlled by their catabolic pathway.
Liu, Yun-xia, Wang, Ji, Zhong, Meng-yu, Sun, Hai-peng, Yu, Jia-yu, Wang, Yi-bin, Zhang, Xue-jiao   +6 more
core   +1 more source

Editorial on “Genome-wide interaction study with body mass index identifies CYP7A1 and GIPR as genetic modulators of metabolic dysfunction-associated steatotic liver disease” [PDF]

Clinical and Molecular Hepatology
Julia Kozlitina
doaj   +1 more source

Maternal high-fat diet orchestrates offspring hepatic cholesterol metabolism via MEF2A hypermethylation-mediated CYP7A1 suppression

Background Maternal overnutrition, prevalent among women of childbearing age, significantly impacts offspring health throughout their lifetime. While DNA methylation of metabolic-related genes mediates the transmission of detrimental effects from ...
Ling Zhang, Jia Zheng, Junqing Zhang, Honghua Wu, Ying Gao, Wenyu Zou, Shixuan Zhang   +6 more
core   +1 more source

Nutritional Regulation of Cholesterol 7alpha Hydroxylase (Cyp7a1) Expression

127 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2009.The combined studies on understanding the molecular basis for the nutritional regulation of CYP7A1 expression may provide new insights into the changes in cholesterol, lipid, and bile
Ponugoti, Bhaskar
core  

Betaine supplementation alleviates corticosterone-induced hepatic cholesterol accumulation through epigenetic modulation of HMGCR and CYP7A1 genes in laying hens

: Excessive corticosterone (CORT) exposure could cause hepatic cholesterol accumulation in chickens and maternal betaine supplementation could decrease hepatic cholesterol deposition through epigenetic modifications in offspring chickens.
Mengwei Zhang, Fanchi Meng, Yun Hu, Ding Li, Xugang Luo, Yulin Wu, Kunpeng Ren   +6 more
core   +1 more source

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MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1

Atherosclerosis, 2022
Huajun Jiang, Bin Hong, Li Wang
exaly  

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Frontiers in Genetics, 2023
Wai-Ping Yau, Han Kiat Ho
exaly  

Human Hepatocyte Nuclear Factors (HNF1 and LXRb) Regulate CYP7A1 in HIV-Infected Black South African Women with Gallstone Disease: A Preliminary Study

Life, 2023
Suman Mewa Kinoo, Savania Nagiah, Bugwan Singh   +2 more
exaly