Results 151 to 160 of about 125,935 (288)

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Immunophenotype and antitumor activity of cytokine-induced killer cells from patients with hepatocellular carcinoma. [PDF]

PLoS One, 2023
Yang CK, Huang CH, Hu CH, Fang JH, Chen TC, Lin YC, Lin CY.   +6 more
europepmc   +1 more source

Modulation of immune responses by human paraininfluenza virus [PDF]

, 2007
Human Parainfluenza virus type 3 (HPIV3) is a key respiratory pathogen responsible for bronchiolitis, pneumonia and croup. The persistent nature of this virus and its ability to reinfect within a short space of time has led to successive failures in the ...
Noone, Cariosa
core  

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche. [PDF]

Front Immunol, 2023
Alberti G, Arsuffi C, Pievani A, Salerno D, Mantegazza F, Dazzi F, Biondi A, Tettamanti S, Serafini M.   +8 more
europepmc   +1 more source

Characterisation of a human herpesvirus 6 variant A 'amplicon' and replication modulation by U94-Rep 'latency gene'.

, 2002
The human herpesvirus 6 (HHV-6) variant A genome has conserved sequences which are signals for initiating lytic replication (origin, 'ori-lyt') and DNA packaging into the virion (pac2/1).
Turner, Simon, Gompels, Ursula, DiLuca, Dario   +2 more
core   +1 more source

Autologous Cytokine-induced Killer Cells [PDF]

, 2020
openaire   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Natural killer cell memory: challenges and opportunities for cancer immunotherapy

Cancer Biology & Therapy
Substantial advancements have been made in recent years in comprehending immune memory, which enhances the secondary response through prior infections.
Yuhua Qu, Anhui Zeng, Yulu Cheng, Shengchun Li   +3 more
doaj   +1 more source

Feasibility of combination of Gun-Chil-Jung and cytokine-induced killer cells-based immunotherapy for terminal hepatocellular carcinoma patient: a case report. [PDF]

Front Pharmacol, 2023
Park CR, Bae HR, Lee GY, Son CG, Cho JH, Cho CK, Lee NH.   +6 more
europepmc   +1 more source