Results 1 to 10 of about 108,055 (293)
Uncoupling cell division and cytokinesis during germline development in metazoans [PDF]
Frontiers in Cell and Developmental Biology, 2022 The canonical eukaryotic cell cycle ends with cytokinesis, which physically divides the mother cell in two and allows the cycle to resume in the newly individualized daughter cells.
Abigail R. Gerhold +4 more
doaj +2 more sources
Role for polo-like kinase 4 in mediation of cytokinesis. [PDF]
, 2019 The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes.
Brugge, Joan S +10 more
core +4 more sources
Cytokinesis in Suspension: A Distinctive Trait of Mesenchymal Stem Cells [PDF]
CellsMesenchymal stem cells (MSCs) have a broad clinical potential, but their selection and expansion on plastic cause unknown purity and phenotypic alterations, reducing therapy efficiency.
Bhavna Rani +2 more
doaj +2 more sources
Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis. [PDF]
ElifeSingh D +5 more
europepmc +2 more sources
mSphere, 2022 Cytokinesis in Trypanosoma brucei occurs unidirectionally from the anterior toward the posterior through mechanisms distinct from those of its human host and is controlled by a signaling pathway comprising evolutionarily conserved and trypanosome ...
Yasuhiro Kurasawa +2 more
doaj +1 more source
The number of cytokinesis nodes in mitotic fission yeast scales with cell size
eLife, 2022 Cytokinesis nodes are assemblies of stoichiometric ratios of proteins associated with the plasma membrane, which serve as precursors for the contractile ring during cytokinesis by fission yeast.
Wasim A Sayyad, Thomas D Pollard
doaj +1 more source
Targeting cytokinesis bridge proteins to kill high-CIN type tumors
Fundamental Research, 2021 As a common feature of tumors, chromosomal instability (CIN) not only forces carcinomatous evolution, but also loads cancer cells with extra pressure through a robust imbalance of genome patterning that may be used for cancer treatment.
Bingteng Xie +11 more
doaj +1 more source
Open Biology, 2022 Cytokinesis in eukaryotes is regulated by a Polo-like kinase-mediated and Aurora B kinase-mediated signalling pathway that promotes the assembly of the actomyosin contractile ring, a cytokinesis machinery conserved across evolution from yeast to humans ...
Yasuhiro Kurasawa +4 more
doaj +1 more source
Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. [PDF]
PLoS Genetics, 2014 Cytokinesis terminates mitosis, resulting in separation of the two sister cells. Septins, a conserved family of GTP-binding cytoskeletal proteins, are an absolute requirement for cytokinesis in budding yeast.
Manoj B Menon +12 more
doaj +1 more source
Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis. [PDF]
PLoS Genetics, 2017 During cytokinesis, a contractile ring generates the constricting force to divide a cell into two daughters. This ring is composed of filamentous actin and the motor protein myosin, along with additional structural and regulatory proteins, including ...
Hyunjung Kim +4 more
doaj +1 more source