Results 91 to 100 of about 101,216 (235)
A Computational Workflow for Cell Line Profiling by Imaging Mass Cytometry
Cytometry Part A, EarlyView.ABSTRACT In single‐cell spatial phenotyping biology, imaging mass cytometry (IMC) stands out as a cutting‐edge, highly multiplexed technology driving discoveries across various disease areas. In vitro profiling relies on tumor‐derived cancer cell lines, known for their diverse morphologies and phenotypes.
Alexandre Bouzekri +2 more
wiley +1 more source
Role for polo-like kinase 4 in mediation of cytokinesis. [PDF]
, 2019 The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes.
Brugge, Joan S +10 more
core +2 more sources
Embryonic development of the Mediterranean starfish Hacelia attenuata
Developmental Dynamics, EarlyView.Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo +3 more
wiley +1 more source
Cortical flow aligns actin filaments to form a furrow
eLife, 2016 Cytokinesis in eukaryotic cells is often accompanied by actomyosin cortical flow. Over 30 years ago, Borisy and White proposed that cortical flow converging upon the cell equator compresses the actomyosin network to mechanically align actin filaments ...
Anne-Cecile Reymann +4 more
doaj +1 more source
Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]
, 2014 The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S. +9 more
core +2 more sources
Interdisciplinary Medicine, EarlyView.We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li +10 more
wiley +1 more source
Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. [PDF]
, 2014 The exocyst serves to tether secretory vesicles to cortical sites specified by polarity determinants, in preparation for fusion with the plasma membrane.
Liu, Dongmei, Novick, Peter
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal +5 more
wiley +1 more source
TSO1 functions in cell division during Arabidopsis flower development [PDF]
, 1997 We describe an Arabidopsis mutant, tso1, which develops callus-like tissues in place of floral organs. The tso1 floral meristem lacks properly organized three cell layers, and the nuclei of these cells are irregular in size and shape.
Liu, Zhongchi +2 more
core
Mitotic centromere-associated kinesin (MCAK) : a potential cancer drug target [PDF]
, 2011 The inability to faithfully segregate chromosomes in mitosis results in chromosome instability, a hallmark of solid tumors. Disruption of microtubule dynamics contributes highly to mitotic chromosome instability.
Sanhaji, Mourad +4 more
core +2 more sources