AbstractCytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in many eukaryotic systems this process is accomplished by an actomyosin contractile ring, the protozoan parasite Trypanosoma brucei displays an unusual mechanism for ...
Farr, H, Gull, K
openaire +4 more sources
Cytokinesis: a logical GAP [PDF]
Two complexes localize to the central spindle and regulate completion of cytokinesis: one, centralspindlin, contains a kinesin-like protein and a Rho-family GAP; the second contains Aurora B kinase. Aurora B kinase is known to regulate localization of centralspindlin and may regulate the activity of the RhoGAP component of centralspindlin.
Masanori Mishima, Michael Glotzer
openaire +3 more sources
Septin filament organization in Saccharomyces cerevisiae. [PDF]
Septins are a family of GTP-binding, membrane-interacting cytoskeletal proteins, highly conserved and essential in all eukaryotes (with the exception of plants). Septins play important roles in a number of cellular events that involve membrane remodeling
Bertin, Aurélie, NOGALES, Eva
core +1 more source
Cytokinesis in Animal Cells [PDF]
Cell division ends with the physical separation of the two daughter cells, a process known as cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately partitioned between the two nascent cells. Cytokinesis is one of the most dramatic changes in cell shape and requires an extensive reorganization of the cell's ...
D'Avino PP, Giansanti MG, Petronczki M
openaire +3 more sources
LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring. [PDF]
The anaphase spindle determines the position of the cytokinesis furrow, such that the contractile ring assembles in an equatorial zone between the two spindle poles.
Price, Kari L, Rose, Lesilee S
core +1 more source
HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis [PDF]
Cytokinesis, the final phase of cell division, is necessary to form two distinct daughter cells with correct distribution of genomic and cytoplasmic materials.
A Konishi+65 more
core +1 more source
Cytokinesis: The Ubc of Positioning [PDF]
A recent analysis of spindle positioning in yeast sheds light on how interactions between microtubules and the cleavage apparatus are modulated through mitosis to promote and maintain proper positioning of the spindle and cleavage plane relative to each other.
Yves Barral, Manuel Hotz
openaire +3 more sources
Cortical Factor Feedback Model for Cellular Locomotion and Cytofission [PDF]
Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoeboid-like locomotion with protrusion of multiple pseudopods, the keratocyte ...
A Nagasaki+45 more
core +4 more sources
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]
Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David+7 more
core +1 more source
The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement [PDF]
AIR9 is a cytoskeleton-associated protein in Arabidopsis thaliana with roles in cytokinesis and cross wall maturation, and reported homologues in land plants and excavate protists, including trypanosomatids.
Almeida Costa, Cristina+7 more
core +2 more sources