Results 41 to 50 of about 101,216 (235)

Regulation of polarised growth in fungi [PDF]

open access: yes, 2008
Polarised growth in fungi occurs through the delivery of secretory vesicles along tracks formed by cytoskeletal elements to specific sites on the cell surface where they dock with a multiprotein structure called the exocyst before fusing with the ...
Adamo   +112 more
core   +1 more source

Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP

open access: yesmBio, 2020
Antibiotic acyldepsipeptides (ADEPs) deregulate ClpP, the proteolytic core of the bacterial Clp protease, thereby inhibiting its native functions and concomitantly activating it for uncontrolled proteolysis of nonnative substrates.
Nadine Silber   +5 more
doaj   +1 more source

Mitosis, Focus on Calcium

open access: yesFrontiers in Physiology, 2022
The transformation of a single fertilised egg into an adult human consisting of tens of trillions of highly diverse cell types is a marvel of biology. The expansion is largely achieved by cell duplication through the process of mitosis.
Charlotte Nugues   +2 more
doaj   +1 more source

Polo-like kinase in trypanosomes: an odd member out of the Polo family [PDF]

open access: yesOpen Biology, 2020
Polo-like kinases (Plks) are evolutionarily conserved serine/threonine protein kinases playing crucial roles during multiple stages of mitosis and cytokinesis in yeast and animals.
Yasuhiro Kurasawa, Tai An, Ziyin Li
doaj   +1 more source

Cytokinesis and cancer

open access: yesFEBS Letters, 2010
Cytokinesis is the final stage of cell division during which the two daughter cells separate completely. Although less well understood than some of the earlier phases of the cell cycle, recent discoveries have shed light on the mechanisms that orchestrate this process, including cleavage furrow formation, midbody maturation and abscission.
Sagona, Antonia P., Stenmark, Harald
openaire   +2 more sources

Polyploid superficial cells that maintain the urothelial barrier are produced via incomplete cytokinesis and endoreplication [PDF]

open access: yes, 2018
Summary: The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and transport of uroplakins, a family of proteins that assemble into a waterproof ...
Batourina, Ekatherina   +13 more
core   +3 more sources

Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity

open access: yeseLife, 2018
Cytokinesis, the physical division of one cell into two, is powered by constriction of an actomyosin contractile ring. It has long been assumed that all animal cells divide by a similar molecular mechanism, but growing evidence suggests that cytokinetic ...
Tim Davies   +6 more
doaj   +1 more source

Live Imaging and Analysis of Meiotic Cytokinesis in Drosophila Testes

open access: yesBio-Protocol
All living organisms require the division of a cell into daughter cells for their growth and maintenance. During cell division, both genetic and cytoplasmic contents are equally distributed between the two daughter cells.
Govind Kunduri, Jairaj Acharya
doaj   +1 more source

Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell division

open access: yeseLife, 2014
Membrane constriction is a prerequisite for cell division. The most common membrane constriction system in prokaryotes is based on the tubulin homologue FtsZ, whose filaments in E. coli are anchored to the membrane by FtsA and enable the formation of the
Piotr Szwedziak   +4 more
doaj   +1 more source

An ATM-CHK2-INCENP pathway prevents chromatin breakage by regulating the abscission checkpoint

open access: yesMolecular & Cellular Oncology, 2021
In response to chromatin bridges, the chromosomal passenger complex (CPC) delays completion of cytokinesis (abscission) to prevent chromosome breakage.
Eleni Petsalaki, George Zachos
doaj   +1 more source

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