Results 71 to 80 of about 85,479 (195)
Abnormal early cleavage events predict early embryo demise: sperm oxidative stress and early abnormal cleavage. [PDF]
, 2014 Human embryos resulting from abnormal early cleavage can result in aneuploidy and failure to develop normally to the blastocyst stage. The nature of paternal influence on early embryo development has not been directly demonstrated although many studies ...
Barker, Christopher M +4 more
core +2 more sources
Mechanics of cytokinesis in eukaryotes [PDF]
Current Opinion in Cell Biology, 2010 Research on eukaryotic cytokinesis using advantageous model systems is rapidly advancing our understanding of most aspects of the process. Cytokinesis is very complicated with more than 100 proteins participating. Both fungi and animal cells use proteins to mark the cleavage site for the assembly of a contractile ring of actin filaments and myosin-II ...
openaire +3 more sources
Exploration, EarlyView.Abnormal spindle‐like microcephaly‐associated protein helps radiotherapy resistant cells to evade spindle checkpoint surveillance and complete cell division after irradiation through destruction of microtubule stability, with subsequent increases in chromosome mis‐segregation and deteriorating chromosomal stability during mitosis to promote ...
Tao Zhong +13 more
wiley +1 more source
Polyploid superficial cells that maintain the urothelial barrier are produced via incomplete cytokinesis and endoreplication [PDF]
, 2018 Summary: The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and transport of uroplakins, a family of proteins that assemble into a waterproof ...
Batourina, Ekatherina +13 more
core +3 more sources
The Journal of Cell Biology, 2005 Cytokinesis proceeds asymmetrically in C. elegans with the furrow invaginating first on one side and then shifting to the other side of the cell, report Audhya et al. on [page 267][1]. This taking of turns, and the structural mechanism that enforces it, may ensure that the furrow is localized in ...
openaire +2 more sources
Exosomes, autophagy, and cancer: A complex triad
International Journal of Cancer, EarlyView.Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés +2 more
wiley +1 more source
Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii
Journal of Applied Toxicology, EarlyView.ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz +12 more
wiley +1 more source
ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]
, 2014 In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
core +2 more sources
Journal of Applied Toxicology, EarlyView.ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps +8 more
wiley +1 more source
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. [PDF]
, 2006 Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic ...
Bishop, Joseph R +4 more
core +2 more sources