Results 101 to 110 of about 3,428 (189)

Genetically similar strains of Escherichia coli O157:H7 isolated from sheep, cattle and human patients [PDF]

, 2012
Conclusions: The same pathogenic subtypes of VTEC O157:H7, including the highly virulent clade 8, appear to be present in both sheep and cattle in Sweden, suggesting strains can circulate freely between ruminant ...
Söderlund, Robert, Aspán, Anna, Hedenström Ingela, Nilsson, Anna, Eriksson, Erik, Nilsson Anna, Hedenström, Ingela, Eriksson Erik, Aspán Anna, Söderlund Robert   +9 more
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Perinuclear Localization of Internalized Outer Membrane Vesicles Carrying Active Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans

, 2012
Aggregatibacter actinomycetemcomitans is implicated in aggressive forms of periodontitis. Similarly to several other Gram-negative species, this organism produces and excretes a cytolethal distending toxin (CDT), a genotoxin associated with ...
Asikainen, Sirkka,, Thay, Bernard,, Oscarsson, Jan,, Pramod Kumar Rompikuntal, Rompikuntal, Pramod Kumar,, Bernard Thay, Khan, Muhammad Khanzeb,, Anna-Maija Penttinen, Wai, Sun Nyunt,, Jan Oscarsson, Muhammad Khanzeb Khan, Sirkka Asikainen, Alanko, Jonna,, Sun Nyunt Wai, Jonna Alanko, Penttinen, Anna-Maija,   +15 more
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Cytolethal Distending Toxin and Its Implication in Periodontal Diseases

Journal of Oral Biosciences, 2005
Abstract Cytolethal distending toxin (Cdt) is a new bacterial toxin that hijacks the control systems of target cells. Cdt is composed of three subunits, CdtA, CdtB and CdtC, all of which form a tripartite complex, and are produced by several bacterial pathogens including Actinobacillus actinomycetemcomitans .
Ohara, Masaru, Sugai, Motoyuki
openaire   +1 more source

Cytolethal distending toxin (Cdt)-producing escherichia coli isolated from a child with bloody diarrhea in Japan

, 2007
In a retrospective analysis by PCR, the cdtI gene encoding the cytolethal distending toxin (Cdt) was detected in Escherichia coli O2:H12 strain isolated from the bloody diarrheal stool specimen of a child.
Nagita, A., Nair, G. B., Yamasaki, S., Takeda, Y., Ramamurthy, T., Asakura, M., Hinenoya, A., Tsukamoto, T.   +7 more
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Cytolethal distending toxin upregulates RANKL expression in Jurkat T‐cells

, 2008
Cytolethal distending toxin, a bacterial exotoxin produced by a number of Gram-negative species, causes growth arrest and morphological alterations in host cells.
TERESA LAGERGÅRD, Belibasakis, George,, Johansson, Anders,, ANDERS JOHANSSON, GEORGIOS N. BELIBASAKIS, MONICA BRAGE, Belibasakis, Georgios N, Brage, Monica, Lagergård, Teresa,, Brage, Monica,, Lagergård, Teresa, Johansson, Anders   +11 more
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Development of two alternative models of campylobacter jejuni infection that more closely mimic the in vivo environment [PDF]

Campylobacter JeJum IS the leading cause of foodborne gastroenteritis worldwide, yet despite the organism's prevalence, relatively little is known about the mechanisms of pathogenesis.
Mills, Dominic Christopher
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A. actinomycetemcomitans Cytolethal Distending Toxin [PDF]

The Journal of Immunology, 2004
Monica, Thelestam, Teresa, Frisan
openaire   +2 more sources

CdtC-Induced Processing of Membrane-Bound CdtA Is a Crucial Step in Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Holotoxin Formation

, 2018
Aggregatibacter actinomycetemcomitans is an oral pathogen causing periodontal disease and bacterial endocarditis. It produces cytolethal distending toxin (CDT) that could damage mammalian cells and tissues.
Keiko Tsuruda, Oranart Matangkasombut, Masaru Ohara, Motoyuki Sugai   +3 more
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Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins

PLOS ONE, 2015
Cytolethal distending toxins (CDTs) are heterotrimeric protein exotoxins produced by a diverse array of Gram-negative pathogens. The enzymatic subunit, CdtB, possesses DNase and phosphatidylinositol 3-4-5 trisphosphate phosphatase activities that induce host cell cycle arrest, cellular distension and apoptosis.
Shandee D Dixon, Melanie M Huynh, Batcha Tamilselvam, Lindsey M Spiegelman, Sophia B Son, Aria Eshraghi, Steven R Blanke, Kenneth A Bradley   +7 more
openaire   +4 more sources

Structural and functional analysis of Helicobacter hepaticus cytolethal distending toxin

, 2009
Helicobacter hepaticus (H. hepaticus) the prototype for enterohepatic Helicobacter species (EHS), colonizes the lower intestinal and hepatobiliary tract of mice and causes typhlocolitis, hepatitis, and hepatocellular carcinoma in susceptible mouse ...
Malimbada Liyanage, Namal Prasanna
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