Results 81 to 90 of about 3,428 (189)

Probiotics Cancer Interaction, Prevention, and Therapy

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote
Mostafa Saebi, Amir Hossein Barjasteh, Mahmoud Mahmoudi, Ramiar Kamal Kheder, Setayesh Ramazanpour, Negar Ebadpour, Afsane Fadaee, Seyed‐Alireza Esmaeili   +7 more
wiley   +1 more source

Evidence for the presence of a receptor for the cytolethal distending toxin (CLDT) of Campylobacter jejuni on CHO and HeLa cell membranes and development of a receptor-based enzyme-linked immunosorbent assay for detection of CLDT

, 1993
Using ligand blotting, it was found that partially purified cytolethal distending toxin prepared from and enterotoxigenic strain of Campylobacter jejuni, bound to two peptides of molecular masses of approximately 59 kDa and 45 kDa and to a single peptide
Bag, Prasant K., Ramamurthy, T., Balakrish Nair, G.   +2 more
core   +1 more source

Bacterial Infections Role in Gynecological Cancers Development: Narrative Review

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Gynecological cancers are among the most common cancers in women that affect female reproductive organs. The most common gynecological cancers are ovarian, cervical, uterine/endometrial, vaginal, and vulvar cancer. Women's reproductive organs have a dynamic and relative microbial balance.
Robab Azargun, Maryam Azargoon, Zahra Asefy, Mina Yekani, Vahideh Tarhriz, Fatemeh Yeganeh, Mohammad Yousef Memar, Shirin Eyvazi   +7 more
wiley   +1 more source

Presence and composition of the cytolethal distending toxin (CDT) locus in the C. difficile strains tested.

, 2015
IM: Internal Medicine; ICU: Intensive Care Unit; PS: Plastic Surgery; GS: General SurgeryPresence and composition of the cytolethal distending toxin (CDT) locus in the C. difficile strains tested.
Elvira Garza-González (401004), Alejandra M. Galván-De los Santos (730759), Héctor J. Maldonado Garza (730762), Francisco J. Bosques-Padilla (730763), Raúl Hernández-García (730758), Daniel López-Barrera (730757), Jorge M. Llaca-Díaz (730761), Adrián Camacho-Ortiz (730756), Samantha M. Flores-Treviño (730760)   +8 more
core   +1 more source

Alteration of homeostasis in pre-osteoclasts induced by Aggregatibacter actinomycetemcomitans CDT

Frontiers in Cellular and Infection Microbiology, 2016
The dysbiotic microbiota associated with aggressive periodontitis includes Aggregatibacter actinomycetemcomitans, the only oral species known to produce a cytolethal distending toxin (AaCDT). Given that CDT alters the cytokine profile in monocytic cells,
Dione eKawamoto, Ellen Sayuri Ando-Sugimoto, Bruno eBueno-Silva, Joseph M. DiRienzo, Marcia Pinto Alves Mayer   +4 more
doaj   +1 more source

The genome and stage‐specific transcriptomes of the carrot weevil, Listronotus oregonensis, reveal adaptive mechanisms for host specialisation and symbiotic interactions

Insect Molecular Biology, Volume 35, Issue 2, Page 126-138, April 2026.
Comprehensive genome and stage‐specific transcriptomes reveal 14,637 genes in Listronotus oregonensis, advancing genetic insights into a key agricultural pest. Compared with related species, L. oregonensis exhibits reduced chemoreceptor gene families but expanded detoxification gene clusters, reflecting its narrow host range and adaptability.
Dave T. Ste‐Croix, Annie‐Ève Gagnon, Benjamin Mimee   +2 more
wiley   +1 more source

Cellular Internalization of Cytolethal Distending Toxin fromHaemophilus ducreyi [PDF]

Infection and Immunity, 2000
ABSTRACTThe chancroid bacteriumHaemophilus ducreyiproduces a toxin (HdCDT) which is a member of the recently discovered family of cytolethal distending toxins (CDTs). These protein toxins prevent the cyclin-dependent kinase cdc2 from being activated, thus blocking the transition of cells from the G2phase into mitosis, with the consequent arrest of ...
X, Cortes-Bratti, E, Chaves-Olarte, T, Lagergård, M, Thelestam   +3 more
openaire   +2 more sources

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, Volume 3, Issue 1, March 2026.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

Aging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell, Eleanor J. Jones, Nima Gharahdaghi, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, Anna K. Simon, Lynne S. Cox, Ghada Alsaleh   +8 more
wiley   +1 more source