Results 71 to 80 of about 128,137 (125)

LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells. [PDF]

Virulence, 2023
Mao W, Wang Z, Wen S, Lin Y, Gu J, Sun J, Wang H, Cao Q, Xu Y, Xu X, Cai X.   +10 more
europepmc   +1 more source

Cytolethal distending toxin upregulates RANKL expression in Jurkat T‐cells

, 2008
Cytolethal distending toxin, a bacterial exotoxin produced by a number of Gram-negative species, causes growth arrest and morphological alterations in host cells.
TERESA LAGERGÅRD, Belibasakis, George,, Johansson, Anders,, ANDERS JOHANSSON, GEORGIOS N. BELIBASAKIS, MONICA BRAGE, Belibasakis, Georgios N, Brage, Monica, Lagergård, Teresa,, Brage, Monica,, Lagergård, Teresa, Johansson, Anders   +11 more
core   +1 more source

Intoxication of mammalian cells by the cytolethal distending toxin of Haemophilus ducreyi : a novel mechanism of action

, 2001
The cytolethal distending toxins (CDTs) are a newly described family of bacterial protein toxins with a novel mechanism of action: DNA damage. Haemophilus ducreyi produces a cytotoxin that belongs to this family.
Ximena Cortes Bratti (19525963)
core   +1 more source

CdtC-Induced Processing of Membrane-Bound CdtA Is a Crucial Step in Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Holotoxin Formation

, 2018
Aggregatibacter actinomycetemcomitans is an oral pathogen causing periodontal disease and bacterial endocarditis. It produces cytolethal distending toxin (CDT) that could damage mammalian cells and tissues.
Keiko Tsuruda, Oranart Matangkasombut, Masaru Ohara, Motoyuki Sugai   +3 more
core   +1 more source

Host-associated variability of the cdtABC operon, coding for the cytolethal distending toxin, in Campylobacter jejuni. [PDF]

Zoonoses Public Health, 2022
Guirado P, Iglesias-Torrens Y, Miró E, Navarro F, Attolini CS, Balsalobre C, Madrid C.   +6 more
europepmc   +1 more source

Presence of Functionally Active Cytolethal Distending Toxin Genes on a Conjugative Plasmid in a Clinical Isolate of Providencia rustigianii. [PDF]

Infect Immun, 2023
Hassan J, Awasthi SP, Hatanaka N, Hoang PH, Nagita A, Hinenoya A, Faruque SM, Yamasaki S.   +7 more
europepmc   +1 more source

Campylobacter jejuni infection impacts host-derived miRNAs targeting bacterial and host genes

Microbiology Spectrum
The intestinal microbiota has been shown to influence host-derived microRNAs (miRNAs), small regulatory RNAs involved in host-pathogen interactions. However, the specific role of individual bacterial species in modulating host extracellular vesicles (EV)-
Siddhi Chitre, Raad Z. Gharaibeh, Rachel C. Newsome, Jinmai Jiang, Andrew Brock, Thomas D. Schmittgen, Christian Jobin   +6 more
doaj   +1 more source

Bacteriophage-Encoding Cytolethal Distending Toxin Type V Gene Induced from Nonclinical Escherichia coli Isolates

, 2011
Cytolethal distending toxin (Cdt) is produced by a variety of pathogenic bacteria, including pathogenic serotypes of Shiga toxin-producing Escherichia coli (STEC). The Cdt family comprises five variants (Cdt-I to Cdt-V) encoded by
Anna Allué-Guardia, Cristina García-Aljaro, Maite Muniesa   +2 more
core   +1 more source

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin-Induces Cell Cycle Arrest in a Glycogen Synthase Kinase (GSK)-3-Dependent Manner in Oral Keratinocytes. [PDF]

Int J Mol Sci, 2022
Shenker BJ, Walker LP, Zekavat A, Korostoff J, Boesze-Battaglia K.   +4 more
europepmc   +1 more source

Coumarin and Quercetin Reduce Ciprofloxacin MIC/MBC and Downregulate the Cytolethal Distending Toxin (cdt) Gene in Ciprofloxacin-Resistant Uropathogenic Escherichia coli [PDF]

Journal of Advanced Biomedical Sciences
Background & Objectives: Uropathogenic Escherichia coli is the major causative agent responsible for urinary tract infections that contribute to a high percentage of community-acquired and nosocomial infections.
Yaqdhan Alnomani
doaj