Results 11 to 20 of about 937,918 (334)

Is there a Role of Intravenous Immunoglobulin in Immunologic Recurrent Pregnancy Loss?

Journal of Immunology Research, 2020
Recurrent pregnancy loss (RPL) commonly refers to three or more miscarriages that occur before 20 weeks of pregnancy. The immunological cause of RPL could be either an auto- or alloimmune-related event or both.
Xiuhua Yang, Tao Meng
doaj   +2 more sources

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

Journal for ImmunoTherapy of Cancer, 2022
Background Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial ...
Maria A Lehn, Trisha M Wise-Draper, Shuchi Gulati, Vinita Takiar, Sarah Palackdharry, Mario Medvedovic, Timothy Stone, Joseph Curry, Vidhya Karivedu, McKenzie Crist, Benyamin Yaniv, Michael Borchers, Bethany Fuhrman, Audrey Crago, Ubaldo Martinez-Outschoorn   +14 more
doaj   +2 more sources

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

OncoImmunology, 2019
Background: Intravesical bacillus Calmette-Guérin (BCG) is the gold standard immunologic agent for treating patients with high-grade non-muscle invasive bladder cancer (NMIBC).
Niannian Ji, Neelam Mukherjee, Edwin E. Morales, Maggie E. Tomasini, Vincent Hurez, Tyler J. Curiel, Getahun Abate, Dan F. Hoft, Xiang-Ru Zhao, Jon Gelfond, Sourindra Maiti, Laurence J.N. Cooper, Robert S. Svatek   +12 more
doaj   +2 more sources

Cytoskeletal stabilization of inhibitory interactions in immunologic synapses of mature human dendritic cells with natural killer cells [PDF]

Blood, 2011
Human mature dendritic cells (DCs) can efficiently stimulate natural killer (NK)-cell responses without being targeted by their cytotoxicity. To understand this important regulatory crosstalk, we characterized the development of the immunologic synapse ...
Barreira da Silva, Rosa, Graf, C, Münz, C   +2 more
core   +2 more sources

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation.

Blood, 2001
Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor cooperation with ...
A. Spriel, J. Leusen, M. Egmond, H.B.P.M. Dijkman, K.J.M. Assmann, Tanya N. Mayadas, J. V. D. Winkel   +6 more
semanticscholar   +1 more source

Altered distribution of mucosal NK cells during HIV infection. [PDF]

, 2012
The human gut mucosa is a major site of human immunodeficiency virus (HIV) infection and infection-associated pathogenesis. Increasing evidence shows that natural killer (NK) cells have an important role in control of HIV infection, but the mechanism(s ...
Alter, G, Berger, CT, Carrington, M, Deeks, SG, Diefenbach, T, Dugast, A-S, Estes, JD, Ghebremichael, M, Hunt, PW, Kwon, D, Liu, Q, Martin, JN, Sciaranghella, G, Sips, M   +13 more
core   +2 more sources

Assessment of intracanal medications cytotoxicity on L929 fibroblast cells

Bioscience Journal, 2016
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias, Felipe de Souza Matos, Nayane Chagas Carvalho, Roque Pacheco de Almeida, Adriano Augusto Melo de Mendonça, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Maria Amália Gonzaga Ribeiro   +6 more
doaj   +3 more sources

Cytotoxicity and genotoxicity of calcium silicate-based cements on an osteoblast lineage

Brazilian Oral Research, 2016
Several calcium silicate-based biomaterials have been developed in recent years, in addition to Mineral Trioxide Aggregate (MTA). The aim of this study was to evaluate the cytotoxicity, genotoxicity and apoptosis/necrosis in human osteoblast cells (SAOS ...
Ana Lívia GOMES-CORNÉLIO, Elisandra Márcia RODRIGUES, Leticia Boldrin MESTIERI, Thaís de Oliveira Rodrigues Sanzovo FALCOSKI, Christiane Pienna SOARES, Juliane Maria GUERREIRO-TANOMARU, Carlos ROSSA JUNIOR, Mário TANOMARU FILHO   +7 more
doaj   +1 more source

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo, Albrechtson, Billing, Boyle, Colombani, Evans, Foon, Franksson, Fu, Greaves, H. Takahashi, J.C. Cicciarelli, Johnson, Kaplan, Machleder, Matell, Medawar, P.I. Terasaki, R. Billing, Starzl, Starzl, Suciu-Foca, T. Starzl, T. Yamaguchi, Terasaki, Y. Iwaki   +25 more
core   +1 more source

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Biomaterials Research, 2023
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to address the donor shortage as well as immunologic rejection attributed to cells in conventional tissue/organ transplantation.
Mohammadreza Kasravi, Armin Ahmadi, Amirhesam Babajani, Radman Mazloomnejad, Mohammad Reza Hatamnejad, Siavash Shariatzadeh, Soheyl Bahrami, Hassan Niknejad   +7 more
doaj   +1 more source