Results 161 to 170 of about 2,965 (199)
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Antihyperglycemic Effects of 3-O-Methyl-D-Chiro-Inositol and D-Chiro-Inositol Associated with Manganese in Streptozotocin Diabetic Rats

Hormone and Metabolic Research, 2000
The acute effects after administration of 3-O-Methyl-D-Chiro-inositol, D-Chiro-inositol and manganese, components of the pH 2.0 putative mediator of insulin action, on plasma glucose were examined in low dose streptozotocin-treated rats. 3-O-Methyl-D-Chiro-inositol at a bolus dose of 5 mg/kg decreased plasma glucose 6% at 120 min (p < 0.05).
M C, Fonteles, M Q, Almeida, J, Larner
exaly   +3 more sources

The D-chiro-inositol paradox in the ovary

Fertility and Sterility, 2011
The D-chiro-inositol-to-myo-inositol ratio is regulated by an insulin-dependent epimerase. Enzyme activity varies among tissues, likely owing to the specific needs of the two different molecules. We hypothesize that in the ovaries of polycystic ovary syndrome patients, epimerase activity is enhanced, leading to a local myo-inositol deficiency which in ...
Gianfranco, Carlomagno   +2 more
openaire   +2 more sources

Synthesis of galactosaminyl d-chiro-inositols

Carbohydrate Research, 2006
All six isomeric D-galactosaminopyranosyl-D-chiro-inositols have been prepared by glycosylation of appropriate penta-O-benzyl-D-chiro-inositols. The three requisite protected D-chiro-inositols were prepared by SmI2-promoted pinacol coupling of dialdehydes derived ultimately from L-arabinose.
Georgia, Marnera, Marc, d'Alarcao
openaire   +2 more sources

Purification and molecular structure of two digalactosyl d-chiro-inositols and two trigalactosyl d-chiro-inositols from buckwheat seeds

Carbohydrate Research, 2001
Two digalactosyl D-chiro-inositols and two trigalactosyl D-chiro-inositols, members of the fagopyritol A series and fagopyritol B series, were isolated from buckwheat (Fagopyrum esculentum Moench) seeds. Structures of the first three were determined by 1H and 13C NMR.
Steadman, KJ, Fuller, DJ, Obendorf, RL
openaire   +4 more sources

Placental expression of d-chiro-inositol phosphoglycans in preeclampsia

Placenta, 2012
Abnormalities in glucose metabolism linked to D-chiro-inostol phosphoglycans (IPGs) have been described in human placentas of preeclamptic women. In this study, a semi-quantitative approach to assess the histological assessment of IPGs revealed no significant differences between early and late onset preeclampsia and gestational age matched controls ...
M, Scioscia   +3 more
openaire   +2 more sources

D‐Chiro‐Inositol Phosphate in a Forest Soil

Soil Science Society of America Journal, 1972
Abstract The previously unidentified “D,L”‐chiro‐inositol phosphate (L'Annunziata and Fuller, 1971) of a Tucson forest soil was identified as the dextrorotatory D‐chiro‐inositol phosphate. An infrared spectrum of the inositol moiety was obtained as evidence for the chiro isomer, additional to the previously ...
Michael F. L'Annunziata   +2 more
openaire   +1 more source

Myoinositol or D-chiro-inositol for PCOS symptoms in adolescents: a narrative review

Journal of Pediatric Endocrinology and Metabolism, 2023
Abstract Background Polycystic ovary syndrome (PCOS) treatment in adolescents currently focuses on lifestyle interventions, with pharmacological treatment options often limited to hormonal contraceptives.
Bibi Zeyah Fatemah Sairally   +3 more
openaire   +2 more sources

Myo-inositol vs. D-chiro inositol in PCOS treatment.

Minerva ginecologica, 2015
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women in fertile age. It is an endocrine and metabolic disorder characterized by oligo-anovulation, hyperandrogenism and insulin-resistance. Various therapeutic approaches have been attempted in PCOS, including diet and the use of pharmacological agents such as oral ...
Formuso C   +2 more
openaire   +3 more sources

Synthesis of fagopyritols A1 and B1 from d-chiro-inositol

Carbohydrate Research, 2004
Fagopyritol A1 (3-O-alpha-d-galactopyranosyl-d-chiro-inositol) and fagopyritol B1 (2-O-alpha-d-galactopyranosyl-d-chiro-inositol) have been synthesized by glycosylation of the diequatorial diol 1,4,5,6-tetra-O-benzoyl-d-chiro-inositol, readily obtained from d-chiro-inositol, with 2,3,4,6-tetra-O-benzyl-d-galactopyranosyl trichloroacetimidate.
M Belén, Cid   +2 more
openaire   +2 more sources

D-Chiro Inositol in Lowering Androgen Levels in Pcos Patients

Pakistan Journal of Medical and Health Sciences, 2022
Background and objectives: PCOS affects the endocrine, metabolic, and reproductive systems, resulting in the production of cysts in the women who have it. When provided, D-chiro inositol, a new therapeutic agent, has the potential to enhance the patient's endocrine profile.
Anza Ashraf   +4 more
openaire   +1 more source

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