Results 21 to 30 of about 1,423 (137)

The use of D-chiro-Inositol in clinical practice.

open access: yesEuropean review for medical and pharmacological sciences, 2021
D-chiro-Inositol has been widely used in clinical practice to induce ovulation in women with polycystic ovary syndrome. Only recent evidence established that this molecule acts through two different mechanisms, with potentially different outcomes.
Gambioli R.   +5 more
openaire   +3 more sources

Physiological, Biochemical, and Structural Bioinformatic Analysis of the Multiple Inositol Dehydrogenases from Corynebacterium glutamicum

open access: yesMicrobiology Spectrum, 2022
Inositols (cyclohexanehexols) comprise nine isomeric cyclic sugar alcohols, several of which occur in all domains of life with various functions. Many bacteria can utilize inositols as carbon and energy sources via a specific pathway involving inositol ...
Paul Ramp   +5 more
doaj   +1 more source

A comparative study of combination of Myo-inositol and D-chiro-inositol versus Metformin in the management of polycystic ovary syndrome in obese women with infertility

open access: yesРепродуктивная эндокринология, 2020
Polycystic ovary syndrome (PCOS) is a symptom complex associated with increased amounts of circulating androgens in females, increased insulin resistance and obesity. The drugs, Myo-inositol, D-chiro-inositol and Metformin, which are insulin sensitizers,
Sujana Thalamati
doaj   +1 more source

Changes in the content of D-chiro-inositol and its α-D-galactosyl derivatives during vegetation and desiccation of common buckwheat (Fagopyrum esculentum Moench)

open access: yesAgronomy Science, 2023
Common buckwheat (Fagopyrum esculentum Moench) is the only crop that contains D-chiro-inositol (DCI) in significant contents in vegetative tissues and its α-D-galactosyl derivatives in seeds.
Lesław Bernard Lahuta   +4 more
doaj   +1 more source

D-chiro-inositol metabolism in diabetes mellitus. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1993
D-chiro-inositol is a rare inositol isomer present in inositol phosphoglycans which are proposed mediators of insulin action. To study D-chiro-inositol metabolism in diabetes mellitus, a sensitive and specific assay was developed using negative-ion chemical ionization gas chromatography/mass spectrometry.
R E, Ostlund   +5 more
openaire   +2 more sources

From Myo-inositol to D-chiro-inositol molecular pathways.

open access: yesEuropean review for medical and pharmacological sciences, 2021
Inositol is a carbocyclic sugar polyalcohol. By epimerization of its hydroxyl groups, nine possible stereoisomers can be generated, two of major physiological and clinical relevance: myo-inositol and D-chiro-inositol. Myo-inositol and D-chiro-inositol are normally stored in kidney, brain and liver and are necessary for functions, such as signal ...
KIANI A. K.   +13 more
openaire   +3 more sources

Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis

open access: yesReproductive Health, 2021
Plain English summary This study aimed to compare the effects of oral insulin sensitizers on endocrine and metabolic profiles in women with polycystic ovary syndrome (PCOS). A random-effects network meta-analysis including 22 trials was conducted.
Han Zhao   +3 more
doaj   +1 more source

Characterization of new polyol/H+ symporters in Debaryomyces hansenii. [PDF]

open access: yesPLoS ONE, 2014
Debaryomyces hansenii is a halotolerant yeast that produces and assimilates a wide variety of polyols. In this work we evaluate polyol transport in D. hansenii CBS 767, detecting the occurrence of polyol/H(+) (and sugar/H(+)) symporter activity, through ...
Iliana Pereira   +4 more
doaj   +1 more source

Exogenously Applied Cyclitols and Biosynthesized Silver Nanoparticles Affect the Soluble Carbohydrate Profiles of Wheat (Triticum aestivum L.) Seedling

open access: yesPlants, 2023
Cyclitols, such as myo-inositol and its isomers and methyl derivatives (i.e., d-chiro-inositol and d-pinitol (3-O-methyl-chiro-inositol)), are classified as osmolytes and osmoprotectants and are significantly involved in plant responses to abiotic ...
Lesław B. Lahuta   +7 more
doaj   +1 more source

Inositol supplementation - known and possible applications

open access: yesJournal of Education, Health and Sport, 2022
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora   +9 more
doaj   +1 more source

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