Results 21 to 30 of about 1,423 (137)
The use of D-chiro-Inositol in clinical practice.
D-chiro-Inositol has been widely used in clinical practice to induce ovulation in women with polycystic ovary syndrome. Only recent evidence established that this molecule acts through two different mechanisms, with potentially different outcomes.
Gambioli R. +5 more
openaire +3 more sources
Inositols (cyclohexanehexols) comprise nine isomeric cyclic sugar alcohols, several of which occur in all domains of life with various functions. Many bacteria can utilize inositols as carbon and energy sources via a specific pathway involving inositol ...
Paul Ramp +5 more
doaj +1 more source
Polycystic ovary syndrome (PCOS) is a symptom complex associated with increased amounts of circulating androgens in females, increased insulin resistance and obesity. The drugs, Myo-inositol, D-chiro-inositol and Metformin, which are insulin sensitizers,
Sujana Thalamati
doaj +1 more source
Common buckwheat (Fagopyrum esculentum Moench) is the only crop that contains D-chiro-inositol (DCI) in significant contents in vegetative tissues and its α-D-galactosyl derivatives in seeds.
Lesław Bernard Lahuta +4 more
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D-chiro-inositol metabolism in diabetes mellitus. [PDF]
D-chiro-inositol is a rare inositol isomer present in inositol phosphoglycans which are proposed mediators of insulin action. To study D-chiro-inositol metabolism in diabetes mellitus, a sensitive and specific assay was developed using negative-ion chemical ionization gas chromatography/mass spectrometry.
R E, Ostlund +5 more
openaire +2 more sources
From Myo-inositol to D-chiro-inositol molecular pathways.
Inositol is a carbocyclic sugar polyalcohol. By epimerization of its hydroxyl groups, nine possible stereoisomers can be generated, two of major physiological and clinical relevance: myo-inositol and D-chiro-inositol. Myo-inositol and D-chiro-inositol are normally stored in kidney, brain and liver and are necessary for functions, such as signal ...
KIANI A. K. +13 more
openaire +3 more sources
Plain English summary This study aimed to compare the effects of oral insulin sensitizers on endocrine and metabolic profiles in women with polycystic ovary syndrome (PCOS). A random-effects network meta-analysis including 22 trials was conducted.
Han Zhao +3 more
doaj +1 more source
Characterization of new polyol/H+ symporters in Debaryomyces hansenii. [PDF]
Debaryomyces hansenii is a halotolerant yeast that produces and assimilates a wide variety of polyols. In this work we evaluate polyol transport in D. hansenii CBS 767, detecting the occurrence of polyol/H(+) (and sugar/H(+)) symporter activity, through ...
Iliana Pereira +4 more
doaj +1 more source
Cyclitols, such as myo-inositol and its isomers and methyl derivatives (i.e., d-chiro-inositol and d-pinitol (3-O-methyl-chiro-inositol)), are classified as osmolytes and osmoprotectants and are significantly involved in plant responses to abiotic ...
Lesław B. Lahuta +7 more
doaj +1 more source
Inositol supplementation - known and possible applications
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora +9 more
doaj +1 more source

