Amperometric Self-Referencing Ceramic Based Microelectrode Arrays for D-Serine Detection
Biosensors, 2018 D-serine is the major D-amino acid in the mammalian central nervous system. As the dominant co-agonist of the endogenous synaptic NMDA receptor, D-serine plays a role in synaptic plasticity, learning, and memory.
Diana Campos-Beltrán +3 more
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Chronic d-serine supplementation impairs insulin secretion [PDF]
Molecular Metabolism, 2018 Objective: The metabolic role of d-serine, a non-proteinogenic NMDA receptor co-agonist, is poorly understood. Conversely, inhibition of pancreatic NMDA receptors as well as loss of the d-serine producing enzyme serine racemase have been shown to ...
Lisa Suwandhi +21 more
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D-serine and serine racemase are associated with PSD-95 and glutamatergic synapse stability
Frontiers in Cellular Neuroscience, 2016 D-serine is an endogenous coagonist at the glycine site of synaptic NMDA receptors (NMDARs), synthesized by serine racemase (SR) through conversion of L-serine. It is crucial for synaptic plasticity and is implicated in schizophrenia.
Hong eLin +6 more
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Clinical and biochemical study of D-serine metabolism among schizophrenia patients
Neuropsychiatric Disease and Treatment, 2017 Hamdy N El-Tallawy,1 Tahia H Saleem,2 Abdallah MAA El-Ebidi,3 Mohammed H Hassan,4 Romany H Gabra,1 Wafaa MA Farghaly,1 Nagwa Abo El-Maali,5 Hoda S Sherkawy3 1Department of Neuropsychiatry, 2Department of Medical Biochemistry and Molecular Biology ...
El-Tallawy HN +7 more
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When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment [PDF]
Microbial Cell, 2016 Sensing environmental stimuli is critically important for bacteria when faced with the multitude of adversities presented within the host. Responding appropriately to these signals and in turn integrating these responses into the regulatory network of ...
James P. R. Connolly, Andrew J. Roe
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Serum d-serine and d-amino acid oxidase (DAO) levels in schizophrenia and related psychotic disorders: a 6-month follow-up study [PDF]
European PsychiatryIntroduction D-serine and the DAO enzyme may impact the NMDA receptor and contribute to schizophrenia, but the exact role and outcomes are not fully understood due to the complexity of the disorder. Objectives We analyzed serum levels of d-serine and
E. Uzun Uysal +3 more
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Fabrication and use of D-serine biosensors for characterising D-serine signalling in rat brain [PDF]
, 2010 D-serine is a co-agonist at NMDA receptors in the brain but the study of this amino\ud acid is restricted by current techniques. I have designed highly sensitive D-serine\ud biosensors that permit accurate real-time recordings of D-serine in the brain in a\ud selective manner.
Bibi, Shakila
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D-serine increases adult hippocampal neurogenesis
Frontiers in Neuroscience, 2013 Adult hippocampal neurogenesis results in the continuous formation of new neurons and is a process of brain plasticity involved in learning and memory. The neurogenic niche regulates the stem cell proliferation and the differentiation and survival of new
Sebastien eSultan +3 more
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Corrigendum: D-serine contributes to seizure development via ERK signaling [PDF]
Frontiers in NeuroscienceTie Ma +8 more
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Frontiers in Psychiatry, 2021 A core symptom that is frequently linked with dysregulation of glutamatergic neurotransmission in regard to schizophrenia is impairment or damage of executive functioning as a component of cognitive deficiency.
Jaromir Hons +10 more
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