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Damage-associated molecular patterns and their receptors in upper airway pathologies
Cellular and Molecular Life Sciences, 2013Inflammation of the nasal (rhinitis) and sinus mucosa (sinusitis) are prevalent medical conditions of the upper airways that are concurrent in many patients; hence the terminology "rhinosinusitis". The disease status is further defined to be "chronic" in case symptoms persist for more than 12 weeks without resolution.
Koen, Van Crombruggen +3 more
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Preeclampsia and damage — associated molecular patterns
Rossiiskii vestnik akushera-ginekologa, 2021V.I. Shcherbakov +2 more
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[Damage-associated molecular patterns and chronic diseases].
Sheng li ke xue jin zhan [Progress in physiology], 2012Molecules of damage-associated molecular patterns (DAMPs) are a class of substances released to intercellular space or peripheral blood by tissues or cells which are stimulated by insults, ischemia or stress. DAMP molecules can be recognized by Toll like receptors, Nod1-like receptors, or Rig-I like receptors and induce autoimmunity or immune tolerance,
Hong-Zhen, Yang +2 more
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[Damage-associated molecular patterns and liver failure].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2017Damage-associated molecular patterns (DAMPs) are a series of intracellular molecules with immunoregulatory activity which are released by the damaged or activated cells and can induce autoimmunity or immune tolerance via pattern recognition receptors.
Y Y, Yan, S, Lin, Y Y, Zhu
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Partial role of TLR4 as a receptor responding to damage-associated molecular pattern
Immunology Letters, 2009Part of pathogen-associated molecular pattern (PAMP) and damage-associated molecular pattern (DAMP) activate antigen-presenting cells through Toll-like receptors (TLRs) to initiate immune responses. However, controversy remains if TLR4 mediates DAMP signaling due to the confounding effects of potential LPS contamination.
Kyung-Mi, Lee, Seung-Yong, Seong
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[DAMPs (damage-associated molecular patterns) and inflammation].
Nihon rinsho. Japanese journal of clinical medicine, 2016Post-ischemic inflammation is re-appraised as an important player in the progression of ischemic stroke. Activation of inflammatory cells via Toll-like receptor 2 (TLR2) and TLR4 is caused by several damage-associated molecular patterns (DAMPs), including high mobility group box-1 (HMGB-1) and heat shock proteins.
Hiroaki, Ooboshi, Takashi, Shichita
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Endocytosis of the damage‐associated molecular pattern receptor PEPR1 is BAK1‐dependent
Journal of Integrative Plant BiologyABSTRACT After cellular damage caused by wounding or pathogens, Arabidopsis thaliana endogenous elicitor peptides (Peps) are released into the apoplast, enhancing innate immunity by directly binding to the membrane‐localized leucine‐rich repeat receptor kinase PEP RECEPTOR1 (
Lucas Alves Neubus Claus +12 more
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DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis
2016This chapter explores the role of some of the key DAMPs in modulating the coagulation and fibrinolytic cascades, how they activate platelets, and modulate platelet functions. Potential mechanisms differentiating disseminated intravascular coagulation from thrombosis are discussed with an emphasis on the generation of procoagulant membrane remnants that
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