Results 101 to 110 of about 59,000 (187)

Biglycan : a multivalent proteoglycan providing structure and signals [PDF]

, 2013
Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Năstase, Mădălina-Viviana, Schäfer, Liliana, Young, Marian F.   +2 more
core  

Mitochondrial damage-associated molecular patterns (DAMPs) in inflammatory bowel disease

, 2018
Background The inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD) are chronic relapsing inflammatory disorders which have a rising incidence and cause significant morbidity. There are currently several treatment options with many more in the drug pipeline, but there are a lack of accurate biomarkers for decisions on ...
openaire   +2 more sources

Innate Immune Surveillance and Recognition of Epigenetic Marks

Epigenomes
The innate immune system protects against infection and cellular damage by recognizing conserved pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Yalong Wang
doaj   +1 more source

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells. [PDF]

BMC Cancer, 2020
Solari JIG, Filippi-Chiela E, Pilar ES, Nunes V, Gonzalez EA, Figueiró F, Andrade CF, Klamt F.   +7 more
europepmc   +1 more source

Taking its TOLL: the role of toll-like receptor 4 in human health and disease, and its potential as a therapeutic target

Frontiers in Immunology
Toll-like receptor 4 (TLR4) is a pattern recognition receptor that binds to pathogen associated molecular patterns (PAMPs) and damage associated molecular patterns (DAMPs). Binding of exogenous or endogenous ligands activates the TLR4 pathway and induces
Phoebe Crammond, Priyanka Hastak, Anthony Delaney, Anthony Delaney, Sarah C. Sasson   +4 more
doaj   +1 more source

Extracellular DNA-Induced Resistance as a Damage Associated Molecular Pattern (DAMP) in plants

Recent studies have underscored the significance of extracellular DNA (eDNA) as a trigger for defense responses in plants. Our results demonstrated that Arabidopsis thaliana responds to the application of eDNA in a species-specific and dosage-dependent manner.
openaire   +1 more source

Diagnostic accuracy of damage-associated molecular patterns (DAMPs) in patients with heart failure with a reduced ejection fraction. [PDF]

J Clin Transl Sci, 2017
Hartupee J, Patel R, Staloch L, Dávila-Román VG, de las Fuentes L, Novak E, Mann DL.   +6 more
europepmc   +1 more source

Inflammatory osteolysis: A conspiracy against bone [PDF]

, 2017
Abu-Amer, Abu-Amer, Anton, Bardin, Beranger, Chen, Christo, Claro, Cobelli, Coll, Dapunt, Deborah V. Novack, Dewhirst, Gabriel Mbalaviele, Georg Schett, Gravallese, Harre, Josse, Jovanovic, Kollias, Lukens, Maitra, McCall, Mukai, Negishi-Koga, Osta, Ozen, Pasco, Robaszkiewicz, Rubbert-Roth, Sanchez, Scianaro, Sharma, Steven L. Teitelbaum, Van Hauwermeiren, Wang, Zaki   +36 more
core   +2 more sources

The egg ribonuclease SjCP1412 accelerates liver fibrosis caused by Schistosoma japonicum infection involving damage-associated molecular patterns (DAMPs). [PDF]

Parasitology
Li QF, Li YX, Yang YY, Dong PP, Mei CJ, Lu JL, Zhang JF, Hua HY, Xiong CR, Yu CX, Song LJ, Yang K.   +11 more
europepmc   +1 more source

TNF/TNF-R1 pathway is involved in doxorubicin-induced acute sterile inflammation [PDF]

, 2013
Aaes, Tania Love, Bachert, Claus, Delvaeye, Tinneke, Heyndrickx, Liesbeth, Kaczmarek, Agnieszka, Krysko, Dmitri, Krysko, Olga, Leybaert, Luc, Vandenabeele, Peter   +8 more
core   +1 more source