Results 161 to 170 of about 59,000 (187)
Some of the next articles are maybe not open access.
2015
Damage-associated molecular pattern molecules (DAMPs) are endogenous molecules that are constitutively expressed and released upon tissue damage, resulting in activation of the immune system. In the absence of injury or infection, DAMPs play important intracellular roles.
Jungo, Kato, Camilla I, Svensson
openaire +2 more sources
Damage-associated molecular pattern molecules (DAMPs) are endogenous molecules that are constitutively expressed and released upon tissue damage, resulting in activation of the immune system. In the absence of injury or infection, DAMPs play important intracellular roles.
Jungo, Kato, Camilla I, Svensson
openaire +2 more sources
Activation of murine γδ T-cells by mitochondrial damage-associated molecular patterns (DAMPS) (45.4)
The Journal of Immunology, 2012Abstract Gamma delta T-cells have been shown to be important in the early immunoinflammatory response to injury, which can be independent of infection. This sterile inflammatory response is in part associated with DAMPs. Mitochondrial DAMPs (MTDs) have been shown to be important in trauma-induced neutrophil activation, but it is unknown ...
Martin Schwacha +2 more
openaire +1 more source
Hypertension, 2012
Aims: Vascular injury including edema and hemorrhage after ischemic stroke is increased in diabetes. High-mobility group box 1 (HMGB1) is a DAMP passively released by necrotic cells that initiates pro-inflammatory signaling through binding to the TLR4 receptor.
Mohammed A Abdelsaid +6 more
openaire +1 more source
Aims: Vascular injury including edema and hemorrhage after ischemic stroke is increased in diabetes. High-mobility group box 1 (HMGB1) is a DAMP passively released by necrotic cells that initiates pro-inflammatory signaling through binding to the TLR4 receptor.
Mohammed A Abdelsaid +6 more
openaire +1 more source
2009
Introduction: Systemic juvenile idiopathic arthritis (sJIA) is chronic childhood arthritis of unknown cause. Novel studies seem to point to deregulation of the innate immune system as the primary pathophysiological mechanism, thus making sJIA an auto-inflammatory disorder. Aim: To explore the involvement of alarmins in the pathogenesis of sJIA Patients
Malčić, Ivan +4 more
openaire
Introduction: Systemic juvenile idiopathic arthritis (sJIA) is chronic childhood arthritis of unknown cause. Novel studies seem to point to deregulation of the innate immune system as the primary pathophysiological mechanism, thus making sJIA an auto-inflammatory disorder. Aim: To explore the involvement of alarmins in the pathogenesis of sJIA Patients
Malčić, Ivan +4 more
openaire
DNA damage and repair in age-related inflammation
Nature Reviews Immunology, 2022Yang Zhao +2 more
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Female erectile tissues and sexual dysfunction after pelvic radiotherapy: A scoping review
Ca-A Cancer Journal for Clinicians, 2022Deborah C Marshall, Mas +2 more
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Nuclear DNA damage signalling to mitochondria in ageing
Nature Reviews Molecular Cell Biology, 2016Evandro Fei Fang +2 more
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The DNA damage response to transcription stress
Nature Reviews Molecular Cell Biology, 2019Hannes Lans +2 more
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DNA damage and the balance between survival and death in cancer biology
Nature Reviews Cancer, 2015Wynand P Roos +2 more
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Therapeutic opportunities within the DNA damage response
Nature Reviews Cancer, 2015Laurence H Pearl +2 more
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