Results 11 to 20 of about 7,628 (201)

Compound Danshen Yeast 1.0

Science of Traditional Chinese Medicine
. Background. Heterologous synthesis presents a promising new approach for accessing the active ingredients of traditional Chinese medicine (TCM), contributing to the conservation of natural medicinal resources.
Rongsheng Li, Jie Wang, Yuanyuan Han, Zhubo Dai   +3 more
doaj   +2 more sources

Research Progress on <i>Salvia miltiorrhiza</i> Bioactive Components Regulating P-Selectin for Microcirculatory Improvement: Potential Implications in Acute Pancreatitis. [PDF]

Mediators Inflamm
Severe acute pancreatitis (SAP) is associated with high morbidity and mortality. Microcirculatory dysfunction is a critical pathological event in this process and a primary contributor to organ failure (OF). Despite the pivotal role of P‐selectin in mediating the adhesion of activated platelets and leukocytes to the vascular endothelium, a process ...
Liu Y, Ao X, Hao W, Wang H, Li L, Wang S, Li J, Liu J, Zhou X, Li Z.   +9 more
europepmc   +2 more sources

The Jasmonate-Responsive SmMPK3-SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza. [PDF]

Plant Biotechnol J
ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Qu R, Wang S, Wang X, Peng J, Guo J, Cui G, Chen T, Chen M, Zhao S, Shen Y.   +9 more
europepmc   +2 more sources

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets [PDF]

, 2017
published_or_final_versio
Cheung, F, Feng, Y, HONG, M, LI, S, Tan, HY, Wang, N   +5 more
core   +7 more sources

Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds. [PDF]

, 2017
Previously, we only apply a traditional Chinese medicine (TCM) Danshen-Chuanxiong-Honghua (DCH) for cardioprotection via anti-inflammation in rats of acute myocardial infarction by occluding coronary artery. Presently, we select not only DCH but also its
Fushun Wang, Jian Wang, Ping Ren, Tingrui Wang, Wan Zheng, Xi Huang, Xi Huang, Xianhua Zhang, Xianhua Zhang, Xinliang Ma   +9 more
core   +7 more sources

Prevention of In-Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation. [PDF]

J Cell Mol Med
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Lei X, Lv C, Zhang Y, Li Z, Shen H, Zhu L.   +5 more
europepmc   +2 more sources

Effect of Danshen for improving clinical outcomes in patients with bladder cancer: a retrospective, population-based study

Frontiers in Pharmacology, 2023
Introduction: Traditional Chinese Medicine (TCM) has a broad application in healthcare, with Danshen being a notable herb used in Eastern medicine for cancer treatment.
Yi-Hsin Chen, Yi-Hsin Chen, Yi-Hsin Chen, Chih-Tsung Chen, Han-Ping Wu, Han-Ping Wu   +5 more
doaj   +1 more source

Danshen extract circumvents drug resistance and represses cell growth in human oral cancer cells

BMC Complementary and Alternative Medicine, 2017
Background Danshen is a common traditional Chinese medicine used to treat neoplastic and chronic inflammatory diseases in China. However, the effects of Danshen on human oral cancer cells remain relatively unknown.
Cheng-Yu Yang, Cheng-Chih Hsieh, Chih-Kung Lin, Chun-Shu Lin, Bo Peng, Gu-Jiun Lin, Huey-Kang Sytwu, Wen-Liang Chang, Yuan-Wu Chen   +8 more
doaj   +1 more source

Salvianolic Acid B Prevents Arsenic Trioxide-Induced Cardiotoxicity In Vivo and Enhances Its Anticancer Activity In Vitro [PDF]

, 2013
Clinical attempts to reduce the cardiotoxicity of arsenic trioxide (ATO) without compromising its anticancer activities remain to be an unresolved issue.
Chen, Rongchang, Dong, Xi, Luo, Yun, Qin, Meng, Sun, Guibo, Sun, Hong, Sun, Xiaobo, Wang, Min, Wu, Ping, Yao, Fan, Zhang, Qiang   +10 more
core   +3 more sources

In Silico investigation of Danshen (Salvia miltiorrhiza) derivatives as potential inhibitor of amyloid beta fibril and design of promising lead compounds as Anti Alzheimer’s drug by pharmacophore modeling [PDF]

Alzheimers Dement
Abstract Background Danshen (Salvia miltiorrhiza) is a kind of rhizome and traditionally being used for the long time in China. In recent years some exceptional experimental works have been done on Danshen derivatives and evidence have been found that several Danshen derivatives are able to inhibit amyloid beta fibril, a pathological hallmark of ...
Saran L.
europepmc   +2 more sources