MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis. [PDF]
, 2015 Tanshinone IIA and cryptotanshinone are two pharmacologically active diterpenoids extracted from the roots of Salvia milthiorriza Bunge, a plant used in Chinese traditional medicine for the treatment of some cardiovascular and cerebrovascular disease ...
Bifulco G. +5 more
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Effects of tanshinone on hyperandrogenism and the quality of life in women with polycystic ovary syndrome: protocol of a double-blind, placebo-controlled, randomised trial. [PDF]
, 2013 published_or_final_versio
Cong, J +6 more
core +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.Novel licorice‐derived compound YCY‐20 attenuates cerebral ischemia–reperfusion injury by suppressing neuronal apoptosis. Mechanistic studies reveal its neuroprotection is mediated through inhibition of the AGE‐RAGE/MAPK pathway, providing a preclinical foundation for stroke therapeutics development.
Jia Luo +8 more
wiley +1 more source
Population level determinants of acute mountain sickness among young men: a retrospective study [PDF]
, 2011 Background Many visitors, including military troops, who enter highland regions from low altitude areas may suffer from acute mountain sickness (AMS), which negatively impacts workable man-hours and increases healthcare costs. The aim of this
Xiaoxiao Li +5 more
core +2 more sources
Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid +7 more
wiley +1 more source
Prevention and modulation of aminoglycoside ototoxicity (Review) [PDF]
, 2008 More than 60 years after their isolation and characterization, aminoglycoside (AG) antibiotics remain powerful agents in the treatment of severe gram-negative, enterococcal or mycobacterial infections.
Ceriani, Isabella +7 more
core +5 more sources
Pifu-xingbing zhenliaoxue zazhiObjective To identify the effective components and key molecules of Yiqi Huoxu compound(YQHX) in the treatment of pulmonary inflammation and fibrosis in scleroderma, providing basis for the development of drug targets for scleroderma.
Menghua HU +9 more
doaj +1 more source
Anti-Amyloidogenic Properties of Some Phenolic Compounds
Biomolecules, 2015 A family of 21 polyphenolic compounds consisting of those found naturally in danshen and their analogues were synthesized and subsequently screened for their anti-amyloidogenic activity against the amyloid beta peptide (Aβ42) of Alzheimer’s disease ...
Afsaneh Porzoor +5 more
doaj +1 more source
Protection of lethal toxicity of endotoxin by Salvia miltiorrhiza BUNGE is via reduction in tumor necrosis factor alpha release and liver injury [PDF]
, 2006 Lipopolysaccharide (LPS) has been implicated as one of the major cause of Gram-negative bacteria-induced sepsis that are life-threatening syndromes occurring in intensive care unit patients. Many natural products derived from medicinal plants may contain
Chan, DKO +4 more
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