Results 181 to 190 of about 14,150 (193)
Some of the next articles are maybe not open access.
Deadenylation and Its Regulation in Eukaryotic Cells
2014Messenger RNA deadenylation is a process that allows rapid regulation of gene expression in response to different cellular conditions. The change of the mRNA poly(A) tail length by the activation of deadenylation might regulate gene expression by affecting mRNA stability, mRNA transport, or translation initiation.
Xiaokan, Zhang +2 more
openaire +2 more sources
The translational capacity of deadenylated ovalbumin messenger RNA
Cell, 1976We present evidence that the poly(A) sequence at the 3' end of ovalbumin mRNA has an effect on its translational efficiency in a reticulocyte lysate cell-free system. Polynucleotide phosphorylase has been used to remove selectively the poly(A) while leaving the rest of the molecule intact.
M T, Doel, N H, Carey
openaire +2 more sources
Regulated deadenylation in vitro.
Methods in enzymology, 2009The 3'-poly(A) tail, found on virtually all mRNAs, is enzymatically shortened by a process referred to as "deadenylation." Deadenylation is a widespread means of controlling mRNA stability and translation. The enzymes involved-so-called deadenylases-are surprisingly diverse. They are controlled by RNA sequences commonly found in 3'-untranslated regions
Aaron C, Goldstrohm +2 more
openaire +1 more source
RNA deadenylation and decay in plants
Journal of Plant Biology, 2013In eukaryotic cells, RNA levels are tightly regulated in a spatio-temporal manner to maintain the protein levels necessary for cell growth, differentiation and division. To cope with developmental and rapid environmental changes, RNAs that are no longer required by the cell undergo degradation via the mRNA decay process. A number of players involved in
Nazia Abbasi +2 more
openaire +1 more source
Chapter 5 Regulated Deadenylation In Vitro
2008The 3'-poly(A) tail, found on virtually all mRNAs, is enzymatically shortened by a process referred to as "deadenylation." Deadenylation is a widespread means of controlling mRNA stability and translation. The enzymes involved-so-called deadenylases-are surprisingly diverse. They are controlled by RNA sequences commonly found in 3'-untranslated regions
Aaron C. Goldstrohm +2 more
openaire +1 more source
A deadenylation negative feedback mechanism governs meiotic metaphase arrest
Nature, 2008In vertebrate oocytes, meiotic progression is driven by the sequential translational activation of maternal messenger RNAs stored in the cytoplasm. This activation is mainly induced by the cytoplasmic elongation of their poly(A) tails, which is mediated by the cytoplasmic polyadenylation element (CPE) present in their 3' untranslated regions.
Eulàlia, Belloc, Raúl, Méndez
openaire +2 more sources
Regulation of mRNA polyadenylation-deadenylation
Molecular Biology Reports, 1987openaire +2 more sources