Results 171 to 180 of about 14,275 (206)

RNA-binding proteins orchestrating immunity in plants. [PDF]

Plant J
Bach-Pages M, Menon A, Wadley B, Castello A, Preston GM.   +4 more
europepmc   +1 more source

The maternal-to-zygotic transition: reprogramming of the cytoplasm and nucleus. [PDF]

Nat Rev Genet
Kojima ML, Hoppe C, Giraldez AJ.
europepmc   +1 more source

We ARE boosting translation: AU-rich elements for enhanced therapeutic mRNA translation. [PDF]

Mol Ther Nucleic Acids
Froechlich G, Sasso E.
europepmc   +1 more source

Coupling mechanisms coordinating mRNA translation with stages of the mRNA lifecycle. [PDF]

RNA Biol
Famà V, Coscujuela Tarrero L, Albanese R, Calviello L, Biffo S, Pelizzola M, Furlan M.   +6 more
europepmc   +1 more source

Uridylation regulates mRNA decay directionality in fission yeast. [PDF]

Nat Commun
Grochowski M, Lipińska-Zubrycka L, Townsend S, Golisz-Mocydlarz A, Zakrzewska-Płaczek M, Brzyżek G, Jurković B, Świeżewski S, Ralser M, Małecki M.   +9 more
europepmc   +1 more source

Targeted mRNA Degradation by Deadenylation-Independent Decapping [PDF]

Molecular Cell, 2004
Modulating the rate of mRNA degradation is a fast and efficient way to control gene expression. In a yeast strain deleted of EDC3, a component of the decapping machinery conserved in eukaryotes, the transcript coding the ribosomal protein Rps28b is specifically stabilized, as demonstrated by microarray and time course experiments.
Gwenael Badis-Bréard, Cosmin Saveanu, Micheline Fromont-Racine   +2 more
exaly   +4 more sources

Transient translational silencing by reversible mRNA deadenylation

Cell, 1992
Tissue-type plasminogen activator (tPA) mRNA is stored, stable and untranslated, in the cytoplasm of fully grown primary mouse oocytes. Dormancy is associated with an unusually short poly(A) tail, and poly(A) tail elongation controls tPA mRNA translational activation during meiotic maturation.
Huarte, Joachim, Stutz, A., O'Connell, M. L., Gubler, P., Belin, Dominique, Darrow, A. L., Strickland, S., Vassalli, Jean-Dominique   +7 more
exaly   +4 more sources

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Deadenylate or activate?

Science, 2020
Immunology When cells are quiescent, they undergo reversible cell cycle arrest and evince low basal metabolism. Naive T cells are normally quiescent until they recognize cognate antigens through T cell receptor–costimulatory molecule signaling. T cell quiescence appears to be an active process, but the mechanistic details are poorly understood.
openaire   +1 more source

Assaying mRNA Deadenylation In Vivo

2014
Deadenylation is the removal of poly(A) tails from mRNA. Here, we present two methods for assaying deadenylation in vivo. The first is a method for measuring bulk poly(A) tail lengths. When combined with a block in transcription, the method can be used for measuring the rate of bulk poly(A) tail shortening.
Claudia, Temme, Elmar, Wahle
openaire   +2 more sources