ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye +4 more
wiley +1 more source
Defensins: The Case for Their Use against Mycobacterial Infections
Human tuberculosis remains a huge global public health problem with an estimated 1/3rd of the population being infected. Defensins are antibacterial cationic peptides produced by a number of cell types, most notably neutrophil granulocytes and epithelial
Haodi Dong +4 more
doaj +1 more source
Expression of defensins in non-infected araneomorph spiders [PDF]
Defensins are a major family of antimicrobial peptides found throughout the phylogenetic tree. From the spider species: Cupiennius salei, Phoneutria reidyi, Polybetes pythagoricus, Tegenaria atrica, and Meta menardi, defensins belonging to the ‘ancestral'
Baumann, Tommy +3 more
core
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian +6 more
wiley +1 more source
Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
core +1 more source
Innate immunity shapes the persistent transmission of plant viruses by insect vectors
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley +1 more source
This review presents the main systemic actions of defensins. Special attention is paid to modulatory effects of defensins on the processes of inflammation and immune response.
A.Ye. Abaturov
doaj +1 more source
Novel Molecules for Intra-Oral Delivery of Antimicrobials to Prevent and Treat Oral Infectious Diseases [PDF]
New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the
Dentino, Andrew R. +2 more
core +1 more source
The Putative Role of Human Peritoneal Adipocytes in the Fight against Bacteria: Synthesis of the Antimicrobial Active Peptide DEFA1-3 [PDF]
Background: Spontaneous peritonitis is a rather rare event, even in peritoneal dialysis (PD). As defensins are natural antimicrobial peptides, we hypothesized that adipocytes as the major constituents of the omentum could play an important role in ...
Groene, Hermann-Josef +5 more
core +1 more source
Toxicity of aqueous extracts of Ilex paraguariensis A.St.‐Hil. about Euphorbia heterophylla L.
Aqueous extracts of Ilex paraguariensis A.St.‐Hil. strongly inhibit Euphorbia heterophylla L. germination and early seedling growth, but show mild phytotoxicity on mature plants, paradoxically promoting biomass via antioxidants. Abstract BACKGROUND The escalating challenge of herbicide‐resistant weeds, exemplified by Euphorbia heterophylla L.
Tamara Alberton da Silva +8 more
wiley +1 more source

