Results 71 to 80 of about 87,250 (304)
An in vitro Study of Drug-induced Degranulation of Human HMC-1 Mast Cells and Rat RBL-2H3 Cells [PDF]
, 2020 Neither codeine nor compound 48/80 produced any significant basophil or mast cell degranulation, whereas the calcium ionophore A23187 triggered a degranulation of both cell lines.
Stig Jacobsson +2 more
core
Animal Research and One Health, EarlyView.This study analyzed the spleen transcriptomes of different chicken breeds, identified key differentially expressed genes (EGR1, FOS, and DUSP1) that regulate resistance to Salmonella infection, and elucidated the underlying regulatory mechanisms, thereby providing new targets for disease‐resistant breeding in poultry.
Zixuan Wang +8 more
wiley +1 more source
World Journal of Otorhinolaryngology-Head and Neck SurgeryBackground Eosinophilic extracellular traps (EETs) are reticular complexes comprising deoxyribonucleic‐Acid (DNA) fibers and granule proteins. Aims EETs play a crucial role in antimicrobial host responses and are pathogenic when overproduced or under ...
Shun‐Yu Wu +5 more
doaj +1 more source
Histologic analysis of CRF-mediated intestinal mast cell degranulation.
, 2013 Treatment of porcine ileal tissues mounted on Ussing chambers with CRF caused and increase in mast cell degranulation as determined by toluidine blue staining. Arrows indicate the release of mast cell granules into surrounding tissues. Sodium cromolyn, a
Jean E. Rivier (317493) +2 more
core +1 more source
Role of phosphoinositide 3-kinases in mast cell activation [PDF]
, 2009 Mast cells are primary effector cells in allergy and chronic inflammation. Class IB (PI3Kγ) and class IA (PI3Kδ) PI3K have been shown to play major roles in mast cell activation: antigen/IgE stimulation triggers autocrine/paracrine activation of mast ...
Collmann, Emilie
core +1 more source
Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease
Arthritis &Rheumatology, EarlyView.Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg +2 more
wiley +1 more source
, 2009 Mei-Fang Yang, Chung-Liang Chien and Kuo-Shan Lu (2002) Compound 48/80- induced degranulation of GnRH-like immunoreactive mast cells in the brain and mesentery of the gerbil. Zoological Studies 41(1): 99-110.
YANG, MEI-FANG;CHIEN, CHUNG-LIANG;LU, KUO-SHYAN +1 more
core
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
, 2002 FcRI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex organized by the linker for activation of T cells (LAT).
Saitoh, S. +19 more
core +1 more source
Ileal granulocyte degranulation for experiments 4–7.
, 2023 On the day of peak Eimeria maxima lesions, ileal segments were collected to assess ileal granulocyte degranulation via β-D-glucuronidase activity. Samples were incubated with 4-MUG at 42°C for 4h and liberated 4-MU was quantified as an indicator of ...
Michael Trombetta (16699179) +4 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long +3 more
wiley +1 more source