Blockade of the Renin-Angiotensin System with Delphinidin, Cyanin, and Quercetin
Planta Medica, 2012Overactivation of the renin-angiotensin system is one of the most important risk factors for the development of hypertension. The use of the crude extracts and/or active compounds, such as anthocyanins and quercetin, of herbal plants that have antihypertensive effects is beneficial for decreasing of blood pressure level.
Warisara, Parichatikanond +2 more
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Delphinidin- and cyanidin-chlorides, promotors of cell aggregation in vitro
Cell Biology International Reports, 1978Delphinidin-chloride and Cyanidinchloride cause cells in cell culture to form aggregates instead of the usual monolayers, without impairing viability or proliferation. The process is reversible.
P G, Schippers, F J, Prop
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Delphinidin accumulation is associated with abnormal flower development in petunias
Phytochemistry, 2004The relative floral anthocyanidin contents of 195 commercial petunias with floral colours other than white and yellow were determined using HPLC, and the presence of five anthocyanidins (cyanidin, peonidin, delphinidin, petunidin, and malvidin) was confirmed. Pelargonidin was not detected, and delphinidin was not a major component.
ANDO, Toshio +6 more
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Delphinidin 3-xylosylrutinoside in petals of Linum grandiflorum
Phytochemistry, 1995Abstract A new anthocyanidin triglycoside was isolated from the scarlet flowers of Linum grandiflorum cv Scarlet Flax as a major anthocyanin. The structure of this pigment was determined to be delphinidin 3-O[2-O(β- d -(xylopyranosyl)-6-O-α- l -rhamnopyranosyl)-β- d -glucopyranoside].
Kenjiro Toki +4 more
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Activity of delphinidin on microvascular damage models in rodents
Phytotherapy Research, 1992AbstractDelphinidin chloride (IdB 1056) was found to possess a significant activity by the intraperitoneal and oral routes in different experimental models of microvascular damage. It antagonized the increase in skin capillary permeability induced by histamine in rats and rabbits, by bradykinin and hyaluronidase in rats and by xylol in mice ...
M. Conti, A. Cristoni, M. J. Magistretti
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Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression
Journal of Agricultural and Food Chemistry, 2016Delphinidin, one of the major anthocyanidins, shows protective effects against a variety of pathologies, including cancer, inflammation, and muscle atrophy. The purpose of this study was to determine the preventive mechanism of delphinidin on disuse muscle atrophy.
Motoki Murata +8 more
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Delphinidin Modulates the DNA-Damaging Properties of Topoisomerase II Poisons
Chemical Research in Toxicology, 2009The anthocyanidin delphinidin (DEL) has recently been shown to inhibit human topoisomerase I and II, without stabilizing the covalent DNA/topoisomerase intermediate [Habermeyer, M., Fritz, J., Barthelmes, H. U., Christensen, M. O., Larsen, M. K., Boege, F., and Marko, D.
Melanie, Esselen +3 more
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Effects of the natural flavonoid delphinidin on diabetic microangiopathy.
Arzneimittel-Forschung, 1995The purpose of the present study was to investigate the effects of the flavonoid delphinidin chloride (CAS 528-53-0, IdB 1056) on diabetic microangiopathy. Hamsters were injected with alloxan and cheek pouch microcirculation was observed by a fluorescent microscopy technique 90 days from alloxan.
BERTUGLIA S. +2 more
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Comparison of the Inhibitory Effects of Delphinidin and Its Glycosides on Cell Transformation
Planta Medica, 2014Although anthocyanins are major forms distributed in many plant foods and promising as chemopreventive source, many molecular data are obtained from anthocyanidins, showing their low bioavailability. This study aims to clarify the inhibitory effects of delphinidin glycosides on cell transformation comparing them to those of delphinidin.
Takayuki, Sogo +7 more
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Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues
Current Pharmaceutical Design, 2019Background: Among polyphenolic compounds suggested to prevent cardiovascular diseases (CVDs) and to explain the “French paradox”, the anthocyanidin delphinidin (Dp) has been reported to support at least partly the vascular beneficial effects of dietary polyphenolic compounds including those from fruits and related products as red wine.
Samuel, Legeay +7 more
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