Results 61 to 70 of about 765 (99)

Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases

open access: yesComputational and Structural Biotechnology Journal
Here, we show that the histone lysine demethylases KDM5A and KDM5B can bind to RNA through interaction with G-quadruplexes, despite neither being categorized as RNA- nor G-quadruplex binding proteins across numerous experimental large-scale and ...
Johanna Luige   +8 more
doaj   +1 more source

Identification and expression analysis of N6-methyltransferase and demethylase in rapeseed (Brassica napus L.)

open access: yesBMC Genomics
Background N 6 -methyladenosine (m6A) modification involves the addition of a methyl group to the nitrogen atom at position six of adenine in RNA. It is the most prevalent type of dynamic internal RNA methylation modification, plays an important role in ...
Xiaoyu Chen   +9 more
doaj   +1 more source

Insights into the m6A demethylases FTO and ALKBH5 : structural, biological function, and inhibitor development

open access: yesCell & Bioscience
N6-methyladenosine (m6A) is dynamically regulated by methyltransferases (termed “writers”) and demethylases (referred to as “erasers”), facilitating a reversible modulation.
Zewei Gao   +4 more
doaj   +1 more source

SMYD family in cancer: epigenetic regulation and molecular mechanisms of cancer proliferation, metastasis, and drug resistance

open access: yesExperimental and Molecular Medicine
Epigenetic modifiers (miRNAs, histone methyltransferases (HMTs)/demethylases, and DNA methyltransferases/demethylases) are associated with cancer proliferation, metastasis, angiogenesis, and drug resistance.
Tae-Su Han   +3 more
doaj   +1 more source

Dealing with demethylases [PDF]

open access: yesNature Chemical Biology, 2012
openaire   +1 more source

KDM6A/B Demethylases in Gut Homeostasis

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2023
Natalia Soshnikova
doaj   +1 more source

Demethylases Need PHDs♦ [PDF]

open access: yesJournal of Biological Chemistry, 2010
openaire   +1 more source

SPECIFICITY OF RABBIT KIDNEY DEMETHYLASE

open access: yesJournal of Biological Chemistry, 1954
M, MORITANI   +6 more
openaire   +2 more sources

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