Results 21 to 30 of about 37,089 (146)

CHARACTERIZATION OF SIGNAL CONDUCTION ALONG DEMYELINATED AXONS BY ACTION-POTENTIAL-ENCODED SECOND HARMONIC GENERATION [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2014
Action-potential-encoded optical second harmonic generation (SHG) has been recently proposed for use in detecting the axonal damage in patients with demyelinating diseases.
ZHI-HUI LUO   +6 more
doaj   +1 more source

Exogenous Antioxidants in Remyelination and Skeletal Muscle Recovery

open access: yesBiomedicines, 2022
Inflammatory, oxidative, and autoimmune responses cause severe damage to the nervous system inducing loss of myelin layers or demyelination. Even though demyelination is not considered a direct cause of skeletal muscle disease there is extensive damage ...
Ricardo Julián Cabezas Perez   +2 more
doaj   +1 more source

Immunological Demyelination Triggers Macrophage/Microglial Cells Activation without Inducing Astrogliosis

open access: yesClinical and Developmental Immunology, 2013
The glial scar formed by reactive astrocytes and axon growth inhibitors associated with myelin play important roles in the failure of axonal regeneration following central nervous system (CNS) injury.
Frank Cloutier   +3 more
doaj   +1 more source

Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Microglia are the resident phagocytic cells of the central nervous system (CNS). During demyelination, a condition in which myelin sheaths are damaged and removed from neurons due to inflammation, microglia can play both harmful and ...
A. Sariol   +9 more
semanticscholar   +1 more source

Astrogliosis During Acute and Chronic Cuprizone Demyelination and Implications for Remyelination

open access: yesASN Neuro, 2012
In multiple sclerosis, microglia/macrophage activation and astrocyte reactivity are important components of the lesion environment that can impact remyelination.
Norah Hibbits   +3 more
doaj   +1 more source

Central Pontine Myelinosis and Osmotic Demyelination Syndrome.

open access: yesDeutsches Ärzteblatt International, 2019
BACKGROUND Osmotic demyelination syndrome (ODS), which embraces central pontine myelinolysis (CPM) and extrapontine myelinosis (EPM), is often underdiagnosed in clinical practice, but can be fatal.
J. Lambeck   +3 more
semanticscholar   +1 more source

Secondary parkinsonism due to osmotic demyelination syndrome: a case report

open access: yesThe Egyptian Journal of Internal Medicine, 2015
Hyponatremia is a common medical problem often found in the elderly and is due to poor intake, medical comorbidities, and medications. Central to the management of this condition is the use of normal and hypertonic saline, besides the use of ...
Waseem R Dar   +4 more
doaj   +1 more source

Mild Traumatic Brain Injury Results in Significant and Lasting Cortical Demyelination

open access: yesFrontiers in Neurology, 2022
Despite contributing to neurocognitive deficits, intracortical demyelination after traumatic brain injury (TBI) is understudied. This study uses magnetic resonance imaging (MRI) to map intracortical myelin and its change in healthy controls and after ...
Sean O. Mahoney   +5 more
doaj   +1 more source

Epilepsy in patients with MOG antibody disease [PDF]

open access: yesАнналы клинической и экспериментальной неврологии, 2021
Introduction. MOG (anti-myelin oligodendrocyte glycoprotein) antibody disease is a group of demyelinating disorders of the central nervous system, in which antibodies attack the glycoproteins on the oligodendrocyte myelin membrane.
Varvara E. Avdeeva, Aleksey S. Kotov
doaj   +1 more source

Clinical manifestations and imaging features of white matter demyelination in older patients

open access: yesJournal of International Medical Research, 2020
Objective To investigate the clinical manifestations and imaging features of older patients with white matter demyelination diagnosed by magnetic resonance imaging (MRI).
Jian Li, Yi-Ming Zhao
doaj   +1 more source

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