Results 41 to 50 of about 94,021 (297)
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
The vagus nerve-dependent lung-brain axis mediates brain demyelination following acute lung injury
Brain, Behavior, & Immunity - HealthPatients with acute lung injury (ALI) often experience psychiatric and neurological symptoms; however, the precise underlying mechanisms remain unclear.
Dan Xu +7 more
doaj +1 more source
A Unified Frequency Domain Model to Study the Effect of Demyelination on Axonal Conduction
, 2016 Multiple sclerosis is a disease caused by demyelination of nerve fibers. In order to determine the loss of signal with the percentage of demyelination, we need to develop models that can simulate this effect. Existing time-based models does not provide a
Saurabh Chaubey, Shikha J. Goodwin
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PRES-like presentation in MOG antibody-related demyelination (MARD)
, 2020 A 33-year-old male presented with a progressive four-week history of frontal headache and left visual field impairment. MRI brain confirmed bilateral, asymmetric, occipital vasogenic oedema, suggestive of posterior reversible encephalopathy syndrome ...
Bhuta, Sandeep +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Pathogenesis of Virus-Induced Demyelination
, 1993 Demyelination is a component of several viral diseases of humans. The best known of these are subacute sclerosing panencephalitis (SSPE) and progressive multifocal leukoencephalopathy (PML).
Fazakerley, JK, Buchmeiert, MJ
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Cortical Demyelination in Multiple Sclerosis [PDF]
, 2008 Cortical demyelination in CNS inflammatory demyelinating diseases is reviewed in an editorial and in a study by Moll NM et al (Neurology 2008;70:336-343)
J Gordon Millichap, Millichap, J. Gordon
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T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Imaging of the optic nerve in acute vision loss—A pictorial review
Kerala Journal of Ophthalmology, 2023 Optic nerves are paired cranial nerves and are unique as they represent the extension of the central nervous system (CNS). It is involved in many cases of acute vision loss, and magnetic resonance imaging (MRI) plays an important role in the detection of
Namrata +5 more
doaj +1 more source