Results 41 to 50 of about 91,619 (289)

CNS demyelination associated with nilotinib

open access: yes, 2023
As treatment options for cancer and autoimmune diseases are developing each day, iatrogenic central demyelination case reports are increasing in number.
Ezgi Erturul   +7 more
core   +1 more source

Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine

open access: yesMolecular Pain, 2010
Background Although neuropathic pain is frequently observed in demyelinating diseases such as Guillain-Barré syndrome and multiple sclerosis, the molecular basis for the relationship between demyelination and neuropathic pain behaviors is poorly ...
Aoki Junken   +8 more
doaj   +1 more source

Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination

open access: yesJournal of Neuroinflammation, 2023
Demyelination occurs in multiple central nervous system (CNS) disorders and is tightly associated with neuroinflammation. Pyroptosis is a form of pro-inflammatory and lytic cell death which has been observed in CNS diseases recently.
Yao Wang   +10 more
doaj   +1 more source

Mild Traumatic Brain Injury Results in Significant and Lasting Cortical Demyelination

open access: yesFrontiers in Neurology, 2022
Despite contributing to neurocognitive deficits, intracortical demyelination after traumatic brain injury (TBI) is understudied. This study uses magnetic resonance imaging (MRI) to map intracortical myelin and its change in healthy controls and after ...
Sean O. Mahoney   +5 more
doaj   +1 more source

Secondary parkinsonism due to osmotic demyelination syndrome: a case report

open access: yesThe Egyptian Journal of Internal Medicine, 2015
Hyponatremia is a common medical problem often found in the elderly and is due to poor intake, medical comorbidities, and medications. Central to the management of this condition is the use of normal and hypertonic saline, besides the use of ...
Waseem R Dar   +4 more
doaj   +1 more source

Clinical manifestations and imaging features of white matter demyelination in older patients

open access: yesJournal of International Medical Research, 2020
Objective To investigate the clinical manifestations and imaging features of older patients with white matter demyelination diagnosed by magnetic resonance imaging (MRI).
Jian Li, Yi-Ming Zhao
doaj   +1 more source

A Unified Frequency Domain Model to Study the Effect of Demyelination on Axonal Conduction

open access: yes, 2016
Multiple sclerosis is a disease caused by demyelination of nerve fibers. In order to determine the loss of signal with the percentage of demyelination, we need to develop models that can simulate this effect. Existing time-based models does not provide a
Saurabh Chaubey, Shikha J. Goodwin
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Central Pontine Demyelination: A Case Report

open access: yesNepal Journal of Neuroscience, 2016
Central Pontine Demyelination is a neurological disease caused by rapidly fl uctuating serum osmolality resulting in severe damage of the myelin sheath of nerve cells in the brainstem, more precisely in the area of pons. This condition is associated with
Manju Maharjan   +4 more
doaj   +1 more source

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

open access: yes, 1987
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
core  

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