Results 41 to 50 of about 117,570 (300)
The vagus nerve-dependent lung-brain axis mediates brain demyelination following acute lung injury
Brain, Behavior, & Immunity - HealthPatients with acute lung injury (ALI) often experience psychiatric and neurological symptoms; however, the precise underlying mechanisms remain unclear.
Dan Xu +7 more
doaj +1 more source
Imaging of the optic nerve in acute vision loss—A pictorial review
Kerala Journal of Ophthalmology, 2023 Optic nerves are paired cranial nerves and are unique as they represent the extension of the central nervous system (CNS). It is involved in many cases of acute vision loss, and magnetic resonance imaging (MRI) plays an important role in the detection of
Namrata +5 more
doaj +1 more source
Osmotic demyelination syndrome [PDF]
BMJ Case Reports, 2014 A 25-year-old man presented with progressive impairment of consciousness, ocular bobbing and tetraparesis. Since the age of 3 he had received substitution therapy for central diabetes insipidus after surgical treatment of a craniopharyngioma. Accidental disruption of his intranasal desmopressin treatment 1 day before admission led to an increase of ...
Christian, Börnke +3 more
openaire +2 more sources
Chemokine expression and viral infection of the central nervous system: regulation of host defense and neuropathology. [PDF]
, 2001 An effective host response against viral infection of the central nervous system (CNS) is the principal factor dictating the outcome of infection. It is the responsibility of the immune response to contain and control viral replication. Paradoxically, it
Lane, TE, Liu, MT
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]
, 2015 BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony +12 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Interruptible demyelination in avian riboflavin deficient neuropathy
Cell & BioscienceBackground and aims The evolution of demyelination in individual internodes remains unclear although it has been noticed the paranodal demyelination precedes internodal demyelination in neuropathies with diverse aetiologies.
Zhao Cai
doaj +1 more source
Frontiers in Cellular Neuroscience, 2023 Intracranial (i.c.) inoculation of susceptible mice with a glial-tropic strain of mouse hepatitis virus (JHMV), a murine coronavirus, results in an acute encephalomyelitis followed by viral persistence in white matter tracts accompanied by chronic ...
Amber Syage +6 more
doaj +1 more source
FSD-C10, a Fasudil derivative, promotes neuroregeneration through indirect and direct mechanisms. [PDF]
, 2017 FSD-C10, a Fasudil derivative, was shown to reduce severity of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), through the modulation of the immune response and induction of neuroprotective molecules in the ...
Chai, Zhi +10 more
core +2 more sources