Results 31 to 40 of about 94,021 (297)

Autotaxin and lysophosphatidic acid₁ receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine

Molecular Pain, 2010
Background Although neuropathic pain is frequently observed in demyelinating diseases such as Guillain-Barré syndrome and multiple sclerosis, the molecular basis for the relationship between demyelination and neuropathic pain behaviors is poorly ...
Aoki Junken, Niwa Masami, Ueda Mutsumi, yano Ryo, Matsushita Yosuke, Uchida Hitoshi, Nagai Jun, Chun Jerold, Ueda Hiroshi   +8 more
doaj   +1 more source

2 mediates demyelination in Huntington's disease

, 2020
Demyelination is a common pathological feature of a large number of neurodegenerative diseases including multiple sclerosis and Huntington's disease (HD). Laquinimod (LAQ) has been found to have therapeutic effects on multiple sclerosis and HD.
Xingxing Chen, Weili Yang, Wei, Wenjie, Bai, Dazhang, Yan Hong, Xiao‐Jiang Li, Su Yang, Chen, Xingxing, Yang, Su, Qiong Liu, Dazhang Bai, Peng Yin, Shihua Li, Yin, Peng, Li, Xiao‐Jiang, Wenjie Wei, Li, Shihua, Liu, Qiong, Yongcheng Pan, Hong, Yan, Pan, Yongcheng, Yang, Weili   +21 more
core   +1 more source

Clinical manifestations and imaging features of white matter demyelination in older patients

Journal of International Medical Research, 2020
Objective To investigate the clinical manifestations and imaging features of older patients with white matter demyelination diagnosed by magnetic resonance imaging (MRI).
Jian Li, Yi-Ming Zhao
doaj   +1 more source

Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination

Journal of Neuroinflammation, 2023
Demyelination occurs in multiple central nervous system (CNS) disorders and is tightly associated with neuroinflammation. Pyroptosis is a form of pro-inflammatory and lytic cell death which has been observed in CNS diseases recently.
Yao Wang, Dilinuer Sadike, Bo Huang, Ping Li, Qiao Wu, Na Jiang, Yongkang Fang, Guini Song, Li Xu, Wei Wang, Minjie Xie   +10 more
doaj   +1 more source

CNS demyelination associated with nilotinib

, 2023
As treatment options for cancer and autoimmune diseases are developing each day, iatrogenic central demyelination case reports are increasing in number.
Ezgi Erturul, Erturul Tokgöz, Ezgi, Saliha Gokce, Kocer, Belgin, Belgin Kocer, Gokce, Saliha, Murat Ucar, Uçar, Murat   +7 more
core   +1 more source

Secondary parkinsonism due to osmotic demyelination syndrome: a case report

The Egyptian Journal of Internal Medicine, 2015
Hyponatremia is a common medical problem often found in the elderly and is due to poor intake, medical comorbidities, and medications. Central to the management of this condition is the use of normal and hypertonic saline, besides the use of ...
Waseem R Dar, Najeeb U Sofi, Muzamil Latief, Imtiyaz A Dar, Moomin Hussain   +4 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Central Pontine Demyelination: A Case Report

Nepal Journal of Neuroscience, 2016
Central Pontine Demyelination is a neurological disease caused by rapidly fl uctuating serum osmolality resulting in severe damage of the myelin sheath of nerve cells in the brainstem, more precisely in the area of pons. This condition is associated with
Manju Maharjan , Pranaya Shrestha, Avinash Chandra, Jemesh S Maharjan, Basant Pant   +4 more
doaj   +1 more source

Spinal dystonia and other spinal movement disorders

Dystonia, 2023
While traditionally considered a disorder of the basal ganglia, brainstem, and cerebellum, multiple reports have shown that spinal cord pathologies may lead to dystonia.
Shlok Sarin, Shlok Sarin, Temitope Lawal, Hesham Abboud, Hesham Abboud   +4 more
doaj   +1 more source

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

, 1987
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
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