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CHARACTERIZATION OF SIGNAL CONDUCTION ALONG DEMYELINATED AXONS BY ACTION-POTENTIAL-ENCODED SECOND HARMONIC GENERATION [PDF]
Action-potential-encoded optical second harmonic generation (SHG) has been recently proposed for use in detecting the axonal damage in patients with demyelinating diseases.
ZHI-HUI LUO+6 more
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Epilepsy in patients with MOG antibody disease [PDF]
Introduction. MOG (anti-myelin oligodendrocyte glycoprotein) antibody disease is a group of demyelinating disorders of the central nervous system, in which antibodies attack the glycoproteins on the oligodendrocyte myelin membrane.
Varvara E. Avdeeva, Aleksey S. Kotov
doaj +1 more source
Demyelination and oligodendrocytes
Although neurological sequelae are attributable to poor regeneration of the central nervous system, oligodendrocytes demonstrate robust regenerative response even in adults. Accumulating evidence indicates that the glial cells identified by surface expression of the proteoglycan NG2 are the cellular source of newly-developed oligodendrocytes following ...
Aki Itoh+4 more
openaire +3 more sources
Central Pontine Myelinosis and Osmotic Demyelination Syndrome.
BACKGROUND Osmotic demyelination syndrome (ODS), which embraces central pontine myelinolysis (CPM) and extrapontine myelinosis (EPM), is often underdiagnosed in clinical practice, but can be fatal.
J. Lambeck+3 more
semanticscholar +1 more source
Background Although neuropathic pain is frequently observed in demyelinating diseases such as Guillain-Barré syndrome and multiple sclerosis, the molecular basis for the relationship between demyelination and neuropathic pain behaviors is poorly ...
Aoki Junken+8 more
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Mild Traumatic Brain Injury Results in Significant and Lasting Cortical Demyelination
Despite contributing to neurocognitive deficits, intracortical demyelination after traumatic brain injury (TBI) is understudied. This study uses magnetic resonance imaging (MRI) to map intracortical myelin and its change in healthy controls and after ...
Sean O. Mahoney+5 more
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The myelin sheath, a lipid‐rich multilamellar membrane of relative stability, both insulates and enhances conduction in nerve axons. A notable feature of myelin‐specific proteins, in particular myelin basic protein, is their susceptibility to prote‐olytic activity and their encephalitogenicity, which induces inflammatory demyelination in the CNS.
W. T. Norton, M. L. Cuzner
openaire +3 more sources
Secondary parkinsonism due to osmotic demyelination syndrome: a case report
Hyponatremia is a common medical problem often found in the elderly and is due to poor intake, medical comorbidities, and medications. Central to the management of this condition is the use of normal and hypertonic saline, besides the use of ...
Waseem R Dar+4 more
doaj +1 more source
Clinical manifestations and imaging features of white matter demyelination in older patients
Objective To investigate the clinical manifestations and imaging features of older patients with white matter demyelination diagnosed by magnetic resonance imaging (MRI).
Jian Li, Yi-Ming Zhao
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Objective: Guillain-Barré syndrome (GBS) is an autoimmune disease characterized by weakness in limbs or cranial nerve innervated muscles. Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is the most common variant.
Jawaid, Wajid+5 more
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