Results 161 to 170 of about 39,830 (289)

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Analysis the bacterial community structure of human cholesterol gallstones by PCR-DGGE

open access: yes四川大学学报. 自然科学版, 2016
In this study, the microbial community of cholesterol gallstones and bile were examined by polymerase chain reaction-denaturing gradient gel electrophoresis (DGGE). The DGGE results showed that there are 13 genera in cholesterol gallstones.
PENG Yu-Hong   +7 more
doaj  

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

open access: yesMed Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji   +10 more
wiley   +1 more source

Searching for Gene Defects by Denaturing Gradient Gel Electrophoresis

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1986
L S, Lerman, K, Silverstein, E, Grinfeld
openaire   +2 more sources

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia   +7 more
wiley   +1 more source

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