Results 31 to 40 of about 11,205,379 (410)
Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients
eLife, 2015 Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (cHCV)
Cécile Alanio +23 more
doaj +1 more source
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells
Journal for ImmunoTherapy of Cancer, 2019 Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor antigens and are administered into the patient with the aim to induce a ...
Kalijn F. Bol +13 more
doaj +1 more source
On the Potential of the Excluded Volume and Auto-Correlation as Neuromorphometric Descriptors [PDF]
Physica A 348 (2005) 317-326, 2005 This work investigates at what degree two neuromorphometric measurements, namely the autocorrelation and the excluded volume of a neuronal cell can influence the characterization and classification of such a type of cells. While the autocorrelation function presents good potential for quantifying the dendrite-dendrite connectivity of cells in mosaic ...
arxiv +1 more source
Targeting Human Dendritic Cells with Lewis X Modified Liposomes [PDF]
, 2010 In this short report, we demonstrate that liposomes bearing the Lewis X trisaccharide on the surface (“Awesosomes”) efficiently target human dendritic cells.
Lucie Kalvodova, Yongmin Zhang
core +2 more sources
Autophagy in dendritic cells [PDF]
Cellular & Molecular Immunology, 2018 Autophagy and immunity share the property of being auto-protective for the organism. Autophagy is an important degradation pathway that buffers nutrient deprivation by recycling macromolecules in organisms from yeast to man. Perturbations in autophagy are associated with inflammation and cancer development.
Ghislat, G., Lawrence, T.
openaire +4 more sources
Systemic bacterial infections affect dendritic cell development and function
International Journal of Medical Microbiology, 2021 Dendritic cells (DCs) are critical in host defense against infection. DC depletion is an early event in the course of sepsis that may impair the host defense mechanisms.
Kristin Bieber +3 more
doaj
Active dendrites enhance neuronal dynamic range [PDF]
PLoS Comput Biol 5(6): e1000402 (2009), 2009 Since the first experimental evidences of active conductances in dendrites, most neurons have been shown to exhibit dendritic excitability through the expression of a variety of voltage-gated ion channels. However, despite experimental and theoretical efforts undertaken in the last decades, the role of this excitability for some kind of dendritic ...
arxiv +1 more source
The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]
, 2012 The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core +3 more sources
The role of CD103+ Dendritic cells in the intestinal mucosal immune system.
Frontiers in Immunology, 2011 While dendritic cells (DC) are central to the induction and regulation of adaptive immunity, these cells are very heterogenous and specific subsets can be characterized based on the expression of cell surface markers and functional properties. Intestinal
Darren Thomas Ruane, Ed Charles Lavelle
doaj +1 more source
MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis [PDF]
, 2018 Background: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
O'Neill, Helen C +2 more
core +2 more sources