Results 31 to 40 of about 822,658 (242)
PLoS ONE, 2013 Dendritic cells are the professional antigen presenting cells of innate immunity and key players in maintaining the balance of immune responses. Studies with dendritic cells are mainly limited by their low numbers in vivo and their difficult maintenance ...
Cornelia Richter +5 more
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Current Opinion in Immunology, 2015 Dendritic cells (DCs) are versatile controllers of the immune system, best known for their potent ability to initiate adaptive immunity. Traditionally, DCs have been defined on the basis of cell morphology, expression of specific markers and select functional attributes such as the ability to migrate to T cell areas of secondary lymphoid organs and ...
Barbara U Schraml, Caetano Reis e Sousa
openaire +3 more sources
Nature Communications, 2019 The Wnt pathway regulates anti-tumour immunity in melanoma. Here, the authors show that, in lung adenocarcinoma, secretion of the ligand Wnt1 induces immune resistance by impairing the ability of dendritic cells to cross-prime T cells, and that blocking ...
Dimitra Kerdidani +14 more
doaj +1 more source
Computational convergence of the path integral for real dendritic morphologies [PDF]
, 2012 Neurons are characterised by a morphological structure unique amongst biological cells, the core of which is the dendritic tree. The vast number of dendritic geometries, combined with heterogeneous properties of the cell membrane, continue to challenge ...
Brand, Samuel +3 more
core +2 more sources
Respiratory Research, 2010 Background Abnormal immune responses are believed to be highly relevant in the pathogenesis of chronic obstructive pulmonary disease (COPD). Dendritic cells provide a critical checkpoint for immunity by their capacity to both induce and suppress immunity.
Yi Eunhee S +5 more
doaj +1 more source
MOLECULAR AND CELLULAR MECHANISMS MEDIATED BY DENDRITIC CELLS INVOLVED IN THE INDUCTION OF TOLERANCE
Медицинская иммунология, 2017 Autoimmune diseases and complications after transplantation operations are major public health problem, as they often lead to deterioration in the quality of life, reduce work capacity and disability in the population.
S. V. Sennikov +3 more
doaj +1 more source
Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]
PLoS ONE, 2014 The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro +5 more
doaj +1 more source
MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis [PDF]
, 2018 Background: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
O'Neill, Helen C +2 more
core +2 more sources
VaccinesThe unprecedented global impact caused by SARS-CoV-2 imposed huge health and economic challenges, highlighting the urgent need for safe and effective vaccines.
Mariângela de Oliveira Silva +11 more
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